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用于与口服避孕药相关的胆管癌的区域碘油化疗

Regional lipiodolized chemotherapy for cholangiocarcinoma associated with oral contraceptives.

作者信息

McAleer J J, Dickey W, Clarke R, Johnston G W, Callender M E

机构信息

Royal Victoria Hospital, Belfast, UK.

出版信息

Postgrad Med J. 1987 Jul;63(741):583-4. doi: 10.1136/pgmj.63.741.583.

DOI:10.1136/pgmj.63.741.583
PMID:2821526
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2428355/
Abstract

We describe a case of cholangiocarcinoma in a young woman, who presented with cholestatic jaundice following oral contraceptive ingestion. Following diagnostic laparotomy she received intra-arterial 'lipiodolized' chemotherapy. Intravenous mitozantrone was given for 2 years and she is asymptomatic, with computed tomographic evidence of tumour response, 27 months after diagnosis. We suggest that this form of treatment is of value for cholangiocarcinoma.

摘要

我们描述了一例年轻女性胆管癌病例,该患者在口服避孕药后出现胆汁淤积性黄疸。诊断性剖腹手术后,她接受了动脉内“碘化油”化疗。静脉注射米托蒽醌持续2年,诊断后27个月,她无症状,计算机断层扫描显示肿瘤有反应。我们认为这种治疗方式对胆管癌有价值。

相似文献

1
Regional lipiodolized chemotherapy for cholangiocarcinoma associated with oral contraceptives.用于与口服避孕药相关的胆管癌的区域碘油化疗
Postgrad Med J. 1987 Jul;63(741):583-4. doi: 10.1136/pgmj.63.741.583.
2
Antitumor effect of lipiodolized doxorubicin on VX2 carcinoma in rabbits.碘油阿霉素对兔VX2癌的抗肿瘤作用。
Jpn J Surg. 1985 Jan;15(1):89-91. doi: 10.1007/BF02469864.
3
[Selective chemoembolization with adriamycin-Urografin-Lipiodol in the treatment of hepatocarcinoma].[阿霉素-泛影葡胺-碘油选择性化疗栓塞治疗肝癌]
Rev Med Chil. 1990 Oct;118(10):1135-7.
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Unresectable fibrolamellar hepatocellular carcinoma treated with intra-arterial lipiodolised doxorubicin. A case report.经动脉注射碘化油阿霉素治疗无法切除的纤维板层型肝细胞癌。病例报告。
S Afr Med J. 1987 Nov 21;72(10):701-3.
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Retrospective study on the effects of lipiodolization before a potentially curative hepatectomy for colorectal liver metastases: long-term results of a pilot study.对结直肠癌肝转移潜在根治性肝切除术前碘油栓塞效果的回顾性研究:一项试点研究的长期结果
Hepatogastroenterology. 2001 May-Jun;48(39):790-3.
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Intra-arterial injection of adriamycin/mitomycin C lipiodol suspension in liver metastases.肝转移瘤内经动脉注射阿霉素/丝裂霉素C碘油混悬液
Acta Radiol. 1987 May-Jun;28(3):275-80.
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Hepatocellular carcinoma: surgical resection versus surgical resection combined with pre- and post-operative locoregional immunotherapy-chemotherapy. A prospective randomized study.肝细胞癌:手术切除与手术切除联合术前及术后局部区域免疫治疗-化疗。一项前瞻性随机研究。
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[Intraarterial and intraportal chemotherapy combined with decollateralization for cholangiocellular carcinoma and metastatic liver cancer].[肝动脉和门静脉化疗联合去血管化治疗胆管细胞癌和转移性肝癌]
Gan To Kagaku Ryoho. 1990 Aug;17(8 Pt 2):1758-62.
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Irresectable hepatoma treated by intrahepatic iodized oil doxorubicin hydrochloride: initial results.经肝内碘化油盐酸阿霉素治疗不可切除肝癌的初步结果。
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[Cases of advanced cholangiocarcinoma showing partial response by the combination chemotherapy including protracted continuous infusion of 5-FU combined with intravenous administration of low-dose leucovorin and intra-arterial administration of MMC and CQ].[晚期胆管癌病例通过联合化疗显示部分缓解,联合化疗包括5-氟尿嘧啶持续长时间静脉滴注、静脉注射低剂量亚叶酸钙以及动脉内注射丝裂霉素和顺铂]
Gan To Kagaku Ryoho. 1991 Dec;18(15):2603-5.

本文引用的文献

1
Hepatocellular carcinoma and oral contraceptives.肝细胞癌与口服避孕药
Br J Cancer. 1983 Sep;48(3):437-40. doi: 10.1038/bjc.1983.210.
2
Hepatic lesions caused by anabolic and contraceptive steroids.合成代谢类固醇和避孕类固醇引起的肝脏病变。
Semin Liver Dis. 1981 May;1(2):116-28. doi: 10.1055/s-2008-1040724.
3
[Primary liver cancer in a woman taking oral contraceptives].[一名服用口服避孕药的女性患原发性肝癌]
Nouv Presse Med. 1980 Feb 9;9(7):456.
4
Biliary carcinoma. A review of 109 cases.
Am J Surg. 1984 Apr;147(4):503-9. doi: 10.1016/0002-9610(84)90013-8.
5
Selective effects of Lipiodolized antitumor agents.
J Surg Oncol. 1984 Mar;25(3):218-26. doi: 10.1002/jso.2930250317.
6
Possible association between benign hepatomas and oral contraceptives.良性肝瘤与口服避孕药之间可能存在的关联。
Lancet. 1973 Oct 27;2(7835):926-9. doi: 10.1016/s0140-6736(73)92594-4.
7
Cancer of the liver and the use of oral contraceptives.肝癌与口服避孕药的使用
Br Med J (Clin Res Ed). 1986 May 24;292(6532):1357-61. doi: 10.1136/bmj.292.6532.1357.