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印度尼西亚雅加达成年患者肺炎链球菌分离株的血清型分布及抗菌药物敏感性

Serotype distribution and antimicrobial susceptibility of Streptococcus pneumoniae isolates from adult patients in Jakarta, Indonesia.

作者信息

Said Wahyu F, Sukoto Edy, Khoeri Miftahuddin M, Kumalawati July, Safari Dodi

机构信息

Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Eijkman Institute for Molecular Biology, Jakarta, Indonesia.

出版信息

J Infect Public Health. 2017 Nov-Dec;10(6):833-835. doi: 10.1016/j.jiph.2017.01.018. Epub 2017 Feb 16.

Abstract

Currently, the data on pneumococcal invasive disease in the Indonesian population are limited. In this study, we investigated the serotype distribution and antimicrobial susceptibility of Streptococcus pneumoniae. These samples were isolated from the sputum of adult patients with non-specific clinical symptoms aged 18-87 years in Jakarta, Indonesia, from August to October 2014. Of the 349 sputum specimens, thirteen isolates were identified as S. pneumoniae strains (4%), with two strains each for serotype 19F, 3, and 15A, and one strain each for serotype/serogroup 13, 23A, 6, 34, 17F, 16F, and untypeable. Resistance to tetracycline was most common with only 5 of 13 strains being susceptible. In conclusion, these data provide an initial in the surveillance of invasive pneumococcus in the Indonesia population.

摘要

目前,关于印度尼西亚人群肺炎球菌侵袭性疾病的数据有限。在本研究中,我们调查了肺炎链球菌的血清型分布及抗菌药物敏感性。这些样本于2014年8月至10月从印度尼西亚雅加达18至87岁有非特异性临床症状的成年患者痰液中分离得到。在349份痰标本中,有13株分离菌被鉴定为肺炎链球菌菌株(4%),其中血清型19F、3和15A各有2株,血清型/血清群13、23A、6、34、17F、16F及不可分型各有1株。对四环素耐药最为常见,13株菌株中只有5株敏感。总之,这些数据为印度尼西亚人群侵袭性肺炎球菌的监测提供了初步信息。

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