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针对婴儿、儿童及成人的家用化妆品的暴露评估。

Exposure assessment of family cosmetic products dedicated to babies, children and adults.

作者信息

Gomez-Berrada M P, Ficheux A S, Dahmoul Z, Roudot A C, Ferret P J

机构信息

Safety Assessment Department, Pierre Fabre Dermo Cosmetique, Allée Camille Soula - BP 74 Vigoulet Auzil, 31322 Castanet Tolosan - Cedex, France.

Laboratoire d'Evaluation du Risque Chimique pour le Consommateur (LERCCo), Université Européenne de Bretagne - Université de Bretagne Occidentale (UEB-UBO), UFR Sciences et Techniques, 6 Av. Victor Le Gorgeu, CS93837, 29238 Brest Cedex 3, France.

出版信息

Food Chem Toxicol. 2017 May;103:56-65. doi: 10.1016/j.fct.2017.02.024. Epub 2017 Feb 17.

Abstract

Very few consumption and exposure data is available for family cosmetic products. The aim of the present study was to assess the consumption and the exposure to family cosmetic products used by babies, children and adults. 10 categories of products were studied: shampoo, shower gel, solid soap, cleansing lotion, emollient foam, emollient bath, cream, milk, balm and lip balm. Consumption data were obtained from 2994 participants (789 babies aged 0-3 years, 837 children aged 4-12 years and 1368 adults aged more than 18 years) included in 87 clinical safety studies. Exposure was performed using a probabilistic method. The implementation of consumption and exposure assessment by age has strengthened this work, as consumption and mainly exposure differences were shown. In fact, babies were always the most exposed to family products, followed by children and adults. These original data will be useful for safety assessors and safety agencies in order to protect consumers.

摘要

关于家用化妆品的消费和接触数据非常少。本研究的目的是评估婴儿、儿童和成人使用的家用化妆品的消费情况和接触情况。研究了10类产品:洗发水、沐浴露、固体肥皂、洁面乳、润肤泡沫、润肤浴、面霜、乳液、香脂和唇膏。消费数据来自87项临床安全性研究中的2994名参与者(789名0至3岁的婴儿、837名4至12岁的儿童和1368名18岁以上的成年人)。接触情况采用概率方法进行评估。按年龄进行消费和接触评估的实施加强了这项工作,因为显示出了消费差异,主要是接触差异。事实上,婴儿始终是接触家用产品最多的群体,其次是儿童和成人。这些原始数据将对安全评估人员和安全机构保护消费者有用。

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