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婴儿震颤综合征:维生素B12作用的再探讨

Infantile tremor syndrome: Role of Vitamin B12 revisited.

作者信息

Gupta Rajesh, Mandliya Jagdish, Sonker Pavan, Patil Vandana, Agrawal Manish, Pathak Ashish

机构信息

Department of Pediatrics, Chirayu Medical College, Bhopal, Madhya Pradesh, India.

Department of Pediatrics, R. D. Gardi Medical College, Ujjain, Madhya Pradesh, India.

出版信息

J Pediatr Neurosci. 2016 Oct-Dec;11(4):305-308. doi: 10.4103/1817-1745.199463.

Abstract

OBJECTIVE

To study the role of Vitamin B12 as an etiological factor in patients of infantile tremor syndrome (ITS).

METHODS

Twelve consecutive admissions of children diagnosed clinically as ITS were assessed. Assessment was done using a predefined pro forma to document patient demographic factors, general examination, systemic examination as well as relevant hematological and biochemical investigations.

RESULTS

Out of the 12 cases of ITS, 6 were males and 6 were females. Two cases had serum B12 levels below reference values, five had levels in low normal range, and remaining five had normal values.

CONCLUSIONS

Role of Vitamin B12 deficiency as an etiological factor in the patients of ITS is inconclusive.

摘要

目的

研究维生素B12作为婴儿震颤综合征(ITS)患者病因学因素的作用。

方法

对12例临床诊断为ITS的连续入院儿童进行评估。使用预先定义的表格进行评估,以记录患者的人口统计学因素、全身检查、系统检查以及相关的血液学和生化检查。

结果

在12例ITS病例中,6例为男性,6例为女性。2例血清B12水平低于参考值,5例处于低正常范围,其余5例正常。

结论

维生素B12缺乏作为ITS患者病因学因素的作用尚无定论。

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引用本文的文献

2
Infantile tremor syndrome: current perspectives.婴儿震颤综合征:当前观点
Res Rep Trop Med. 2019 Jul 5;10:103-108. doi: 10.2147/RRTM.S180604. eCollection 2019.

本文引用的文献

1
Infantile tremor syndrome -- down but not out.婴儿震颤综合征——虽受打击但未被淘汰。
Indian Pediatr. 2015 Mar 8;52(3):249-50. doi: 10.1007/s13312-015-0619-9.
4
Infantile "meningo-encephalitic" syndrome.婴儿“脑膜脑炎”综合征
Indian J Pediatr. 1960 Feb;27:49-54. doi: 10.1007/BF02896818.
7
Vitamin B12 deficiency: a cause of abnormal movements in infants.
Pediatrics. 1997 Feb;99(2):255-6. doi: 10.1542/peds.99.2.255.
10
Tremor syndrome in children.儿童震颤综合征
Indian Pediatr. 1969 Aug;6(8):550-6.

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