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原发性脊髓硬膜外原始神经外胚层肿瘤:1例罕见病例

Primary intraspinal extradural primitive neuroectodermal tumor: A rare case.

作者信息

Rege Shrikant V, Tadghare Jitendra, Patil Harshad, Narayan Sharadendu

机构信息

Department of Neurosurgery, Sri Aurobindo Medical College and PG Institute, Indore, Madhya Pradesh, India.

出版信息

J Pediatr Neurosci. 2016 Oct-Dec;11(4):351-354. doi: 10.4103/1817-1745.199460.

DOI:10.4103/1817-1745.199460
PMID:28217164
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5314855/
Abstract

Primitive neuroectodermal tumors (PNETs) are aggressive childhood malignancies and are difficult to treat. Primary intraspinal PNETs are rare. These patients have poor prognosis with short survival time even after surgery and chemoradiation. As there are no standard guidelines exist for the management of these tumors, a multidisciplinary approach has been employed with varying success. According to the review of literature, only few cases of primary intraspinal extradural PNETs have been reported. Herein, author has described a case of intraspinal, extradural PNET.

摘要

原始神经外胚层肿瘤(PNETs)是侵袭性儿童恶性肿瘤,难以治疗。原发性脊柱内PNETs很罕见。这些患者预后较差,即使经过手术和放化疗,生存时间也很短。由于目前尚无针对这些肿瘤治疗的标准指南,因此采用了多学科方法,但效果各异。根据文献综述,仅报道了少数原发性脊柱内硬膜外PNETs病例。在此,作者描述了一例脊柱内硬膜外PNETs病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c274/5314855/bc7d1f14db5c/JPN-11-351-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c274/5314855/8b1a0e7a2789/JPN-11-351-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c274/5314855/de847d970edc/JPN-11-351-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c274/5314855/bc7d1f14db5c/JPN-11-351-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c274/5314855/8b1a0e7a2789/JPN-11-351-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c274/5314855/de847d970edc/JPN-11-351-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c274/5314855/bc7d1f14db5c/JPN-11-351-g003.jpg

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本文引用的文献

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Peripheral primitive neuroectodermal tumor of the cervical spine.颈椎周围原始神经外胚层肿瘤
Surg Neurol Int. 2012;3:91. doi: 10.4103/2152-7806.99938. Epub 2012 Aug 21.
2
Ganglioneuroblastoma of the thoracic spinal cord: a very rare case report.胸段脊髓节细胞神经母细胞瘤:1例极罕见病例报告
Acta Medica (Hradec Kralove). 2012;55(1):50-2. doi: 10.14712/18059694.2015.76.
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Multimodal therapy of an intramedullary cervical primitive neuroectodermal tumor in an adult.成人颈椎髓内原始神经外胚层肿瘤的多模态治疗
J Clin Oncol. 2012 Jan 10;30(2):e15-8. doi: 10.1200/JCO.2011.38.6474. Epub 2011 Dec 5.
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Primary primitive neuroectodermal tumor of the conus medullaris in an elderly patient: a case report and review of the literature.老年患者圆锥原发性原始神经外胚层肿瘤:一例报告并文献复习
Case Rep Oncol. 2011 May;4(2):267-74. doi: 10.1159/000323263. Epub 2011 May 24.
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Eur J Radiol. 2011 Nov;80(2):426-31. doi: 10.1016/j.ejrad.2010.06.005. Epub 2010 Jun 29.
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Incidence patterns for ependymoma: a surveillance, epidemiology, and end results study.室管膜瘤的发病模式:一项监测、流行病学及最终结果研究。
J Neurosurg. 2009 Apr;110(4):725-9. doi: 10.3171/2008.9.JNS08117.
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Descriptive epidemiology of primary spinal cord tumors.原发性脊髓肿瘤的描述性流行病学
J Neurooncol. 2008 Apr;87(2):173-9. doi: 10.1007/s11060-007-9507-z. Epub 2007 Dec 15.
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Pediatric intramedullary spinal cord tumors. Critical review of the literature.小儿脊髓内肿瘤。文献综述。
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9
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10
The cerebellar medulloblastoma and its relationship to primitive neuroectodermal tumors.小脑髓母细胞瘤及其与原始神经外胚层肿瘤的关系。
J Neuropathol Exp Neurol. 1983 Jan;42(1):1-15.