Department of Radiology, The Second Affiliated Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong, China.
Eur J Radiol. 2011 Nov;80(2):426-31. doi: 10.1016/j.ejrad.2010.06.005. Epub 2010 Jun 29.
To retrospectively review CT and MRI findings in a series of six intraspinal primitive neuroectoderal tumors and to find out their radiological features.
CT and MRI of six patients with surgically and pathologically proved intraspinal primitive neuroectoderal tumor were retrospectively reviewed. The tumor location, morphological features, signal intensity, calcification, contrast enhancement characteristics, involvement of paraspinal soft tissues and adjacent bony structures were assessed.
Of six patients, four had extradural lesions and two had intradural, extramedullary lesions. Most lesions were well defined and manifested heterogeneous iso- or hypo-intense signal on T1-weighted imaging and hyper-intense signal on T2-weighted imaging and moderate attenuation on CT, and were heterogeneously enhanced after contrast enhancement. The lesion extending through the intervertebral foramen with a large paraspinal soft tissue mass formed was found in four patients and vertebral bone involvement was seen in four patients.
Although imaging findings are not specific of intraspinal primitive neuroectoderal tumor, this diagnosis could be suggested when MR imaging depicts an intradural, extramedullary or extradural large well-circumscribed mass which extends out from intervertebral foramen and invades paraspinal soft tissues or vertebral bones in a young patient.
回顾性分析 6 例椎管内原始神经外胚层肿瘤的 CT 和 MRI 表现，探讨其影像学特征。
回顾性分析 6 例经手术和病理证实的椎管内原始神经外胚层肿瘤患者的 CT 和 MRI 资料。评估肿瘤的位置、形态特征、信号强度、钙化、强化特点、累及椎旁软组织和邻近骨结构的情况。
6 例患者中，4 例为硬膜外病变，2 例为硬膜内、髓外病变。大多数病变边界清楚，T1WI 呈不均匀等或低信号，T2WI 呈高信号，CT 呈中度衰减，增强后不均匀强化。4 例患者可见病变通过椎间孔延伸，形成较大的椎旁软组织肿块，4 例患者可见椎体骨受累。
尽管影像学表现不具有特异性，但当 MRI 显示出一个从椎间孔延伸出来的、边界清楚的、较大的硬膜内、髓外或硬膜外肿块，并侵犯椎旁软组织或椎体时，可提示诊断为椎管内原始神经外胚层肿瘤。对于年轻患者，这一诊断尤其需要考虑。
