Lv Hu, Han Cui-Hong, Sun Xue-Jun, Liu Wen-Wu
Department of Anaesthesiology, Fudan University Shanghai Cancer Center, Shanghai, China.
Department of Pathology, the First Hospital of Jining City, Jining, Shandong Province, China.
Med Gas Res. 2016 Dec 30;6(4):212-218. doi: 10.4103/2045-9912.196903. eCollection 2016 Oct-Dec.
In recent years, hyperbaric oxygen (HBO) has been used in the treatment of a lot of diseases such as decompression sickness, arterial gas embolism, carbon dioxide poisoning, soft tissue infection, refractory osteomyelitis, and problematic wound, but little is known about its application in liver transplantation. Although several studies have been conducted to investigate the protective effects of HBO on liver transplantation and liver preservation, there are still some controversies on this issue, especially its immunomodulatory effect. In this short review, we briefly summarize the findings supporting the application of HBO during liver transplantation (including donors and recipients).
近年来,高压氧(HBO)已被用于治疗多种疾病,如减压病、动脉气体栓塞、二氧化碳中毒、软组织感染、难治性骨髓炎和难愈合伤口,但关于其在肝移植中的应用却知之甚少。尽管已经进行了多项研究来探讨HBO对肝移植和肝脏保存的保护作用,但在这个问题上仍然存在一些争议,尤其是其免疫调节作用。在这篇简短的综述中,我们简要总结了支持在肝移植期间(包括供体和受体)应用HBO的研究结果。