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人类丘脑腹后外侧核中轴突性多葡聚糖体与衰老的关系

Axonal polyglucosan body in the ventral posterolateral nucleus of the human thalamus in relation to ageing.

作者信息

Mizutani T, Satoh J, Morimatsu Y

机构信息

Department of Clinical Neuropathology, Tokyo Metropolitan Institute for Neurosciences, Japan.

出版信息

Acta Neuropathol. 1987;74(1):9-12. doi: 10.1007/BF00688332.

DOI:10.1007/BF00688332
PMID:2821730
Abstract

Axonal polyglucosan bodies in myelinated axons in the ventral posterolateral nucleus of the human thalamus (VPL) are described. These axonal inclusions were distributed exclusively in the dorsolateral part of the caudal VPL, and their arrangement may be associated with fibres originating from the gracile nucleus. They were not observed in patients under age of 50, and appeared to increase in number and size with advancing age. It is suggested that axonal polyglucosan bodies are an ageing phenomenon of the secondary sensory fibres.

摘要

本文描述了人类丘脑腹后外侧核(VPL)中髓鞘轴突内的轴突多聚葡萄糖体。这些轴突内含物仅分布于尾侧VPL的背外侧部分,其排列可能与薄束核发出的纤维有关。在50岁以下的患者中未观察到它们,且随着年龄的增长,其数量和大小似乎会增加。提示轴突多聚葡萄糖体是次级感觉纤维的一种老化现象。

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本文引用的文献

1
ULTRASTRUCTURE OF CORPORA AMYLACEA.淀粉样体的超微结构
J Neuropathol Exp Neurol. 1965 Jan;24:25-39. doi: 10.1097/00005072-196501000-00003.
2
Thalamic relay to motor cortex: afferent pathways from brain stem, cerebellum, and spinal cord in monkeys.丘脑向运动皮层的投射:猴子中来自脑干、小脑和脊髓的传入通路
J Neurophysiol. 1980 Sep;44(3):532-54. doi: 10.1152/jn.1980.44.3.532.
3
Projections of the cerebellar and dorsal column nuclei upon the thalamus of the rhesus monkey.恒河猴小脑和薄束核在丘脑上的投射。
定量分析阻塞性睡眠呼吸暂停患者海马结构内齿状核的大小和区域分布。
Sci Rep. 2021 Oct 22;11(1):20892. doi: 10.1038/s41598-021-99795-8.
4
Update on polyglucosan storage diseases.多黏糊精贮积症的最新进展。
Virchows Arch. 2019 Dec;475(6):671-686. doi: 10.1007/s00428-019-02633-6. Epub 2019 Jul 30.
5
Corpora amylacea in human hippocampal brain tissue are intracellular bodies that exhibit a homogeneous distribution of neo-epitopes.人脑海马组织中的细胞内体是一种表现出新型表位均匀分布的细胞内体。
Sci Rep. 2019 Feb 14;9(1):2063. doi: 10.1038/s41598-018-38010-7.
6
Exploring the elusive composition of corpora amylacea of human brain.探索人脑齿状核的难以捉摸的组成成分。
Sci Rep. 2018 Sep 10;8(1):13525. doi: 10.1038/s41598-018-31766-y.
7
Corpora Amylacea in Neurodegenerative Diseases: Cause or Effect?神经退行性疾病中的淀粉样体:原因还是结果?
Int J Neurol Neurother. 2015;2(3). doi: 10.23937/2378-3001/2/2/1031. Epub 2015 Aug 28.
8
Polyglucosan bodies in sural nerve biopsies.
Acta Neuropathol. 1990;80(5):554-7. doi: 10.1007/BF00294618.
J Comp Neurol. 1981 Jan 1;195(1):25-50. doi: 10.1002/cne.901950105.
4
Axonal dystrophy in the gracile nucleus of man.人类薄束核中的轴索性营养不良
Acta Neuropathol. 1967 Aug 2;9(1):1-6. doi: 10.1007/BF00688153.
5
Hallervorden-Spatz disease and infantile neuroaxonal dystrophy. Ultrastructural observations, anatomical pathology and nosology.哈勒沃登-施帕茨病与婴儿神经轴索性营养不良。超微结构观察、解剖病理学与疾病分类学。
J Neurol Sci. 1973 Sep;20(1):7-23. doi: 10.1016/0022-510x(73)90114-7.
6
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7
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Virchows Arch A Pathol Anat Histol. 1974;364(4):297-301. doi: 10.1007/BF00432727.
8
Intra-axonal corpora amylacea in the CNS.
Acta Neuropathol. 1977 Feb 28;37(2):165-7. doi: 10.1007/BF00692062.
9
Intra-axonal Corpora amylacea in ventral and lateral horns of the spinal cord.
Acta Neuropathol. 1975;31(2):151-8. doi: 10.1007/BF00688149.
10
Anatomical observations on the dorsal column nuclei, their thalamic projection and the cytoarchitecture of some somatosensory thalamic nuclei in the monkey.对猴子背柱核、其丘脑投射以及一些躯体感觉丘脑核的细胞构筑的解剖学观察。
J Comp Neurol. 1978 Mar 1;178(1):17-48. doi: 10.1002/cne.901780103.