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肌纤维母细胞瘤的临床病理评估:一项在两家医院开展的研究

Clinicopathologic evaluation of myofibroblastoma: A study in two hospitals.

作者信息

Kim Seul Ki, Lee Ji Sun, Hong Su Been, Lee Jung Ryeol, Jee Byung Chul, Suh Chang Suk, Kim Seok Hyun

机构信息

Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea.; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.

Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Korea.

出版信息

Obstet Gynecol Sci. 2017 Jan;60(1):74-78. doi: 10.5468/ogs.2017.60.1.74. Epub 2017 Jan 19.

DOI:10.5468/ogs.2017.60.1.74
PMID:28217675
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5313367/
Abstract

OBJECTIVE

To report various anatomic locations and clinical characteristics of pathologically proven myofibroblastoma in Koran patients.

METHODS

Pathologic reports of patients who underwent surgeries at two centers between April 2003 and March 2016 were retrieved from the electronic medical record system of the hospital. Pathologic reports were included after performing a search using the keyword "myofibroblastoma".

RESULTS

The cohort consisted of 11 subjects and included eight female and three male individuals. The patients' ages ranged from 9 to 66 years. Tumors were located in the vagina in three patients and presented in the breast in seven patients. One case presented with an abdominal mass. The tumors ranged in mean size from 4.0 to 53.0 mm. Despite a relatively long-term follow-up, no case had evidence of tumor recurrence.

CONCLUSION

We evaluated the various anatomic locations of pathologically proven myofibroblastoma in Korean patients. As an extremely rare tumor, physicians should pay special attention to differential diagnosis. Surgical resection is the preferred method for a cure, and the recurrence rate is extremely low.

摘要

目的

报告经病理证实的韩国患者肌成纤维细胞瘤的各种解剖位置及临床特征。

方法

从医院电子病历系统中检索2003年4月至2016年3月期间在两个中心接受手术患者的病理报告。使用关键词“肌成纤维细胞瘤”进行检索后纳入病理报告。

结果

该队列由11名受试者组成,包括8名女性和3名男性。患者年龄在9至66岁之间。3例肿瘤位于阴道,7例位于乳腺。1例表现为腹部肿块。肿瘤平均大小在4.0至53.0毫米之间。尽管进行了相对长期的随访,但无一例有肿瘤复发的证据。

结论

我们评估了经病理证实的韩国患者肌成纤维细胞瘤的各种解剖位置。作为一种极其罕见的肿瘤,医生应特别注意鉴别诊断。手术切除是首选的治愈方法,复发率极低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b941/5313367/fbf5d0493e74/ogs-60-74-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b941/5313367/38961b1c60a7/ogs-60-74-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b941/5313367/fbf5d0493e74/ogs-60-74-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b941/5313367/38961b1c60a7/ogs-60-74-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b941/5313367/fbf5d0493e74/ogs-60-74-g002.jpg

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本文引用的文献

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Mammary myofibroblastoma in the right lateral abdominal wall.右侧腹壁乳腺肌纤维母细胞瘤。
World J Surg Oncol. 2016 Feb 24;14:55. doi: 10.1186/s12957-016-0796-6.
2
Mammary-type Myofibroblastoma: Clinicopathologic Characterization in a Series of 143 Cases.乳腺型肌纤维母细胞瘤:143例病例系列的临床病理特征
Am J Surg Pathol. 2016 Mar;40(3):361-7. doi: 10.1097/PAS.0000000000000540.
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Myofibroblastoma: report of a rare entity in the pediatric population.
Pediatr Dev Pathol. 2012 Nov-Dec;15(6):499-506. doi: 10.2350/12-05-1204-CR.1. Epub 2012 Aug 17.
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Superficial cervicovaginal myofibroblastoma: fourteen cases of a distinctive mesenchymal tumor arising from the specialized subepithelial stroma of the lower female genital tract.浅表宫颈阴道肌纤维母细胞瘤:14例源自女性下生殖道特殊上皮下间质的独特间叶性肿瘤。
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Breast tumors with myofibroblastic differentiation: clinico-pathological observations in myofibroblastoma and myofibrosarcoma.具有肌成纤维细胞分化的乳腺肿瘤:肌纤维母细胞瘤和肌纤维肉瘤的临床病理观察
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Myofibroblastoma of the breast. Sixteen cases of a distinctive benign mesenchymal tumor.乳腺肌纤维母细胞瘤。16例一种独特的良性间叶性肿瘤。
Am J Surg Pathol. 1987 Jul;11(7):493-502. doi: 10.1097/00000478-198707000-00001.