Lorange Ellen, Harmanli Oz, Cao Q Jackie, Jones Keisha A
Department of Obstetrics and Gynecology, Tufts University School of Medicine, Baystate Medical Center, 759 Chestnut Street, S-1681, Springfield, MA 01199, USA.
J Reprod Med. 2013 Jul-Aug;58(7-8):344-6.
Both ectopic prostate tissue in the female genital tract and vaginal myofibroblastoma have rarely been reported in the literature. Tamoxifen use has been associated with the development of vaginal myofibroblastoma.
A 76-year-old, multiparous woman who had taken tamoxifen for breast cancer presented with postmenopausal bleeding and a vaginal mass. Endometrial work-up revealed a benign polyp, and the polypoid tumor in the vagina was found to be a myofibroblastoma harboring ectopic prostatic glands.
To our knowledge this is the first case of these two rare pathologic entities occurring together. Of note, this patient also had a history of tamoxifen therapy, like some of the previous patients with vaginal myofibroblastoma.
女性生殖道中的异位前列腺组织和阴道肌成纤维细胞瘤在文献中均鲜有报道。他莫昔芬的使用与阴道肌成纤维细胞瘤的发生有关。
一名76岁、多产的女性，因乳腺癌服用他莫昔芬，出现绝经后出血和阴道肿物。子宫内膜检查显示为良性息肉，阴道内的息肉样肿瘤被发现是一个含有异位前列腺腺体的肌成纤维细胞瘤。
据我们所知，这是这两种罕见病理实体同时出现的首例病例。值得注意的是，该患者也有他莫昔芬治疗史，与之前一些阴道肌成纤维细胞瘤患者情况相同。
