Bozso S J, Nagendran Je, Gill R S, Freed D H, Nagendran Ja
Division of Cardiac Surgery, Department of Surgery, University of Alberta, Edmonton, AB, Canada; Mazankowski Alberta Heart Institute, Edmonton, AB, Canada.
Peter Lougheed Centre - Department of Surgery, University of Calgary, Calgary, AB, Canada.
Transplant Proc. 2017 Mar;49(2):344-347. doi: 10.1016/j.transproceed.2016.12.002.
Increasing prevalence of obesity has led to a rise in the number of prospective obese heart and lung transplant recipients. The optimal management strategy of obese patients with end-stage heart and lung failure remains controversial. This review article discusses and provides a summary of the literature surrounding the impact of obesity on outcomes in heart and lung transplantation. Studies on transplant obesity demonstrate controversy in terms of morbidity and mortality outcomes and obesity pre-transplantation. However, the impact of obesity on outcomes seems to be more consistently demonstrated in lung rather than heart transplantation. The ultimate goal in heart and lung transplantation in the obese patient is to identify those at highest risk of complication that may warrant therapies to mitigate risk by addressing comorbid conditions.
肥胖患病率的不断上升导致预期进行心脏和肺移植的肥胖受者数量增加。肥胖的终末期心肺衰竭患者的最佳管理策略仍存在争议。这篇综述文章讨论并总结了有关肥胖对心脏和肺移植结果影响的文献。关于移植肥胖的研究在发病率、死亡率结果以及移植前肥胖方面存在争议。然而，肥胖对结果的影响在肺移植中似乎比在心脏移植中更一致地得到证实。肥胖患者心脏和肺移植的最终目标是识别那些并发症风险最高的患者，这些患者可能需要通过治疗合并症来降低风险。
