University Hospital Erasme, Interventional Neuroradiology, Brussels, Belgium.
J Neurointerv Surg. 2018 Feb;10(2):127-132. doi: 10.1136/neurintsurg-2016-012964. Epub 2017 Feb 20.
To evaluate the clinical and anatomical results of treatment of intracranial aneurysms (IA) with the Woven EndoBridge (WEB) device, with emphasis on mid term and long term follow-up.
Between November 2010 and November 2015, we retrospectively identified, in our prospectively maintained database, all patients treated by WEB device placement for an IA at three institutions. Clinical charts, procedural data, and angiographic results were reviewed.
48 patients with 49 IAs were identified. There were 35 women and 13 men with a mean age of 57 years (range 35-76 years). All IA were wide necked. Mean aneurysm size was 8.6 mm. There were 44 unruptured IA and 5 ruptured IA. During endovascular treatment (EVT), adjunctive devices were used in 22.4% of procedures. A good clinical outcome (modified Rankin Scale score ≤2) was achieved in 44/48 patients (92%). There was no mortality. Mean follow-up was 25 months (range 3-72 months; median 24 months). Between mid term and long term follow-up, occlusion was stable in 19/23 IA (82.6%), improved in 2/23 IA (8.7%), and worsened in 2/23 IA (8.7%). Retreatment was performed in 8/49 IA (16.3%). At the latest available follow-up, there were 34/47 (72.3%) complete occlusions and 13/47 (27.7%) neck remnants.
Our study suggests that EVT of IA with the WEB device provides adequate and stable long term occlusion.
评估 WEB 装置治疗颅内动脉瘤（IA）的临床和解剖学结果，重点关注中期和长期随访。
在 2010 年 11 月至 2015 年 11 月期间，我们在三个机构的前瞻性维护数据库中回顾性地确定了所有接受 WEB 装置治疗 IA 的患者。回顾了临床图表、程序数据和血管造影结果。
共确定了 48 例 49 个 IA 的患者。其中 35 例为女性，13 例为男性，平均年龄为 57 岁（范围 35-76 岁）。所有 IA 均为宽颈。平均动脉瘤大小为 8.6mm。有 44 个未破裂的 IA 和 5 个破裂的 IA。在血管内治疗（EVT）期间，22.4%的手术中使用了辅助装置。44/48 例患者（92%）获得了良好的临床结局（改良 Rankin 量表评分≤2）。无死亡。平均随访时间为 25 个月（范围 3-72 个月；中位数 24 个月）。在中期和长期随访之间，19/23 个 IA 的闭塞稳定（82.6%），2/23 个 IA 的闭塞改善（8.7%），2/23 个 IA 的闭塞恶化（8.7%）。对 49 个 IA 中的 8 个（16.3%）进行了再次治疗。在最新的随访中，有 34/47 个（72.3%）完全闭塞，13/47 个（27.7%）存在瘤颈残留。
我们的研究表明，WEB 装置治疗 IA 的 EVT 可提供充分且稳定的长期闭塞。
