Folk Gillian A, Nelson Brenda L
Academy of Our Lady of Peace, San Diego, CA, USA.
Department of Head and Neck Pathology, NMCSD, San Diego, CA, USA.
Head Neck Pathol. 2017 Dec;11(4):513-516. doi: 10.1007/s12105-017-0797-y. Epub 2017 Feb 20.
A 44-year-old female presented to her general dentist with the chief complaint of a painful mouth sore of 2 weeks duration. Clinical examination revealed an irregularly shaped ulcer of the buccal and lingual attached gingiva of the anterior mandible. A biopsy was performed and microscopic evaluation revealed histoplasmosis. Histoplasmosis, caused by Histoplasma capsulate, is the most common fungal infection in the United States. Oral lesions of histoplasmosis are generally associated with the disseminated form of histoplasmosis and may present as a fungating or ulcerative lesion of the oral mucosa. The histologic findings and differential diagnosis for oral histoplasmosis are discussed.
一名44岁女性前往她的普通牙医处就诊,主诉有一个持续2周的疼痛性口腔溃疡。临床检查发现下颌前部颊侧和舌侧附着龈有一个形状不规则的溃疡。进行了活检,显微镜评估显示为组织胞浆菌病。组织胞浆菌病由荚膜组织胞浆菌引起,是美国最常见的真菌感染。组织胞浆菌病的口腔病变通常与播散型组织胞浆菌病相关,可能表现为口腔黏膜的蕈样或溃疡性病变。本文讨论了口腔组织胞浆菌病的组织学表现及鉴别诊断。