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Two Cases of Neisseria meningitidis Proctitis in HIV-Positive Men Who Have Sex with Men.两例感染HIV的男同性恋者患脑膜炎奈瑟菌直肠炎的病例
Emerg Infect Dis. 2017 Mar;23(3):542-543. doi: 10.3201/eid2303.161039.
2
[Proctitis in an HIV-infected male who have sex with men].一名男男性行为的HIV感染者的直肠炎
Med Clin (Barc). 2016 May 20;146(10):468-9. doi: 10.1016/j.medcli.2015.11.017. Epub 2015 Dec 31.
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Unencapsulated penicillin-resistant ST-53 clonal complex strain causing symptomatic proctitis in an HIV-negative man who has sex with men: A case report.无包膜青霉素耐药 ST-53 克隆复合体菌株引起的男性同性恋者直肠炎：一例报告。
Int J STD AIDS. 2022 Sep;33(10):933-935. doi: 10.1177/09564624221113686. Epub 2022 Jul 5.
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Molecular epidemiology of Neisseria meningitidis isolates from an outbreak of meningococcal disease among men who have sex with men, Chicago, Illinois, 2003.2003年伊利诺伊州芝加哥男男性行为者群体中脑膜炎球菌病暴发时分离出的脑膜炎奈瑟菌的分子流行病学研究
J Clin Microbiol. 2007 Nov;45(11):3768-70. doi: 10.1128/JCM.01190-07. Epub 2007 Aug 29.
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Prior (Nm) proctitis does not prevent (Ng) proctitis among men who have sex with men (MSM).既往的（Nm）直肠炎并不能预防男男性行为者（MSM）中的（Ng）直肠炎。
Sex Transm Infect. 2023 May;99(3):215. doi: 10.1136/sextrans-2023-055759. Epub 2023 Feb 23.
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Meningococcal disease and sexual transmission: urogenital and anorectal infections and invasive disease due to Neisseria meningitidis.脑膜炎奈瑟菌病与性传播：泌尿生殖道和直肠感染以及奈瑟脑膜炎奈瑟菌引起的侵袭性疾病。
Lancet. 2020 Jun 13;395(10240):1865-1877. doi: 10.1016/S0140-6736(20)30913-2.
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Oral and anal carriage of Neisseria meningitidis among sexually active HIV-infected men who have sex with men in Denmark 2014-15.2014-15 年丹麦有性活跃的 HIV 感染男男性行为者中脑膜炎奈瑟菌的口腔和肛门携带情况。
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The contribution of Mycoplasma genitalium to the aetiology of sexually acquired infectious proctitis in men who have sex with men.解脲支原体对男男性行为者获得性直肠传染性炎症病因学的贡献。
Clin Microbiol Infect. 2016 Mar;22(3):260-5. doi: 10.1016/j.cmi.2015.11.016. Epub 2015 Dec 12.
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Proctitis and prostatitis by Neisseria meningitidis among MSM: A case series.男男性行为者中由脑膜炎奈瑟菌引起的直肠炎和前列腺炎：病例系列
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Urethritis caused by novel Neisseria meningitidis serogroup W in man who has sex with men, Japan.日本男性同性恋者中由新型W群脑膜炎奈瑟菌引起的尿道炎
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Sexually Transmitted Infections Treatment Guidelines, 2021.《2021年性传播感染治疗指南》
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Urethritis in a Thai Male.一名泰国男性的尿道炎
J Health Sci Med Res JHSMR. 2021;39(3):251-255. doi: 10.31584/jhsmr.2020773.
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Tracking a serial killer: Integrating phylogenetic relationships, epidemiology, and geography for two invasive meningococcal disease outbreaks.追踪连环杀手：整合系统发育关系、流行病学和地理信息学分析两起侵袭性脑膜炎奈瑟菌病暴发。
PLoS One. 2018 Nov 28;13(11):e0202615. doi: 10.1371/journal.pone.0202615. eCollection 2018.

本文引用的文献

1
Notes from the Field: Increase in Neisseria meningitidis-Associated Urethritis Among Men at Two Sentinel Clinics - Columbus, Ohio, and Oakland County, Michigan, 2015.实地记录：2015年俄亥俄州哥伦布市和密歇根州奥克兰县两家哨点诊所男性中脑膜炎奈瑟菌相关性尿道炎病例增加
MMWR Morb Mortal Wkly Rep. 2016 Jun 3;65(21):550-2. doi: 10.15585/mmwr.mm6521a5.
2
Evolutionary Events Associated with an Outbreak of Meningococcal Disease in Men Who Have Sex with Men.与男男性行为者中脑膜炎球菌病暴发相关的进化事件
PLoS One. 2016 May 11;11(5):e0154047. doi: 10.1371/journal.pone.0154047. eCollection 2016.
3
Orogenital transmission of Neisseria meningitidis serogroup C confirmed by genotyping techniques.通过基因分型技术证实的C群脑膜炎奈瑟菌的口生殖器传播。
Eur J Clin Microbiol Infect Dis. 2005 Jan;24(1):51-3. doi: 10.1007/s10096-004-1257-7.
4
Antigenic and/or phase variation of PorA protein in non-subtypable Neisseria meningitidis strains isolated in Spain.在西班牙分离出的不可分型脑膜炎奈瑟菌菌株中PorA蛋白的抗原性和/或相变异
J Med Microbiol. 2004 Jun;53(Pt 6):515-518. doi: 10.1099/jmm.0.05517-0.
5
Etiology of clinical proctitis among men who have sex with men.男男性行为者临床直肠炎的病因
Clin Infect Dis. 2004 Jan 15;38(2):300-2. doi: 10.1086/380838. Epub 2003 Dec 19.
6
Antigenic diversity of meningococcal enterobactin receptor FetA, a vaccine component.脑膜炎球菌肠杆菌素受体FetA（一种疫苗成分）的抗原多样性
Microbiology (Reading). 2003 Jul;149(Pt 7):1849-1858. doi: 10.1099/mic.0.26131-0.
7
Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms.多位点序列分型：一种用于鉴定致病微生物群体内克隆的便捷方法。
Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3140-5. doi: 10.1073/pnas.95.6.3140.
8
Histology of rectal gonorrhoea in men, with a note on anorectal infection with Neisseria meningitidis.男性直肠淋病的组织学，兼论脑膜炎奈瑟菌引起的肛门直肠感染
J Clin Pathol. 1983 May;36(5):511-4. doi: 10.1136/jcp.36.5.511.

两例感染HIV的男同性恋者患脑膜炎奈瑟菌直肠炎的病例

Two Cases of Neisseria meningitidis Proctitis in HIV-Positive Men Who Have Sex with Men.

作者信息

Gutierrez-Fernandez José, Medina Verónica, Hidalgo-Tenorio Carmen, Abad Raquel

出版信息

Emerg Infect Dis. 2017 Mar;23(3):542-543. doi: 10.3201/eid2303.161039.

DOI:10.3201/eid2303.161039
PMID:28221124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5382739/
Abstract

We report 2 cases from Spain of infectious proctitis caused by Neisseria meningitidis in HIV-positive men who have sex with men. Genetic characterization of the isolates showed that they are unusual strains not found in other more frequent meningococcal locations. This finding suggests an association between specific strains and anogenital tract colonization.

摘要

我们报告了2例来自西班牙的病例，是由脑膜炎奈瑟菌引起的感染性直肠炎，患者为男男性行为的HIV阳性者。对分离株的基因特征分析表明，它们是在其他更常见的脑膜炎球菌感染部位未发现的罕见菌株。这一发现表明特定菌株与肛门生殖道定植之间存在关联。