Turku Centre for Biotechnology, University of Turku, FIN-20520 Turku, Finland.
Turku Centre for Biotechnology, University of Turku, FIN-20520 Turku, Finland; Department of Biochemistry and Food Chemistry, University of Turku, Turku, Finland.
Curr Biol. 2017 Feb 20;27(4):R158-R161. doi: 10.1016/j.cub.2016.12.036.
A new study shows that endothelial cells use synaptic-like machinery to control polarized secretion and deposition of newly synthesised fibronectin. This process is coupled to active integrin recycling to the same locations and is fundamental for vascular development in zebrafish.
一项新的研究表明,内皮细胞利用类似突触的机制来控制新合成的纤维连接蛋白的极化分泌和沉积。这个过程与整合素的主动回收到相同的位置相偶联,对于斑马鱼的血管发育是至关重要的。