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腹腔镜袖状胃切除术时同期行胆囊切除术的安全性:美国外科医师学会国家外科质量改进计划数据库分析

Safety of concomitant cholecystectomy at the time of laparoscopic sleeve gastrectomy: analysis of the American College of Surgeons National Surgical Quality Improvement Program database.

作者信息

Dakour-Aridi Hanaa N, El-Rayess Hebah M, Abou-Abbass Hussein, Abu-Gheida Ibrahim, Habib Robert H, Safadi Bassem Y

机构信息

Department of Surgery, American University of Beirut, Beirut, Lebanon.

Department of Internal Medicine, American University of Beirut, Beirut, Lebanon.

出版信息

Surg Obes Relat Dis. 2017 Jun;13(6):934-941. doi: 10.1016/j.soard.2016.12.012. Epub 2016 Dec 23.

Abstract

BACKGROUND

The indication and safety of concomitant cholecystectomy (CC) during bariatric surgical procedures are topics of controversy. Studies on the outcomes of CC with laparoscopic sleeve gastrectomy (LSG) are scarce.

OBJECTIVES

To assess the safety and 30-day surgical outcomes of CC with LSG.

METHODS

A retrospective analysis of the American College of Surgeons National Surgical Quality Improvement Program database 2010 to 2013. Univariate and multivariate analyses were used.

RESULTS

Between 2010 and 2013, 21,137 patients underwent LSG; of those 422 (2.0%) underwent CC (LSG+CC), and the majority (20,715 [98%]) underwent LSG alone. Patients in both groups were similar in age, sex distribution, baseline weight, and body mass index. The average surgical time was significantly higher, by 33 minutes, in the LSG+CC cohort. No differences were noted between the groups with regard to overall 30-day mortality and length of hospital stay. CC increased the odds of any adverse event (5.7% versus 4.0%), but the difference did not reach statistical significance (odds ratio 1.49, P = .07). Two complications were noted to be significantly higher with LSG+CC, namely bleeding (P = .04) and pneumonia (P = .02).

CONCLUSION

CC during LSG appears to be a safe procedure with slightly increased risk of bleeding and pneumonia compared with LSG alone. When factoring the potential risk and cost of further hospitalization for deferred cholecystectomy, these data support CC for established gallbladder disease.

摘要

背景

减重手术期间同期行胆囊切除术(CC)的适应证及安全性是存在争议的话题。关于腹腔镜袖状胃切除术(LSG)同期行CC结局的研究较少。

目的

评估LSG同期行CC的安全性及30天手术结局。

方法

对美国外科医师学会国家外科质量改进计划2010年至2013年数据库进行回顾性分析。采用单因素和多因素分析。

结果

2010年至2013年期间,21137例患者接受了LSG;其中422例(2.0%)接受了CC(LSG+CC),而大多数(20715例[98%])仅接受了LSG。两组患者在年龄、性别分布、基线体重和体重指数方面相似。LSG+CC队列的平均手术时间显著延长33分钟。两组在30天总体死亡率和住院时间方面无差异。CC增加了发生任何不良事件的几率(5.7%对4.0%),但差异未达到统计学意义(优势比1.49,P = 0.07)。有两种并发症在LSG+CC组显著更高,即出血(P = 0.04)和肺炎(P = 0.02)。

结论

与单纯LSG相比,LSG同期行CC似乎是一种安全的手术,但出血和肺炎风险略有增加。考虑到延期胆囊切除术进一步住院的潜在风险和费用,这些数据支持对已确诊胆囊疾病行CC。

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