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胰十二指肠切除术:在正中弓状韧带松解无效后对腹腔干进行二次支架置入及再次手术,作为同期肝动脉重建的替代方案。

Pancreaticoduodenectomy: Secondary stenting of the celiac trunk after inefficient median arcuate ligament release and reoperation as an alternative to simultaneous hepatic artery reconstruction.

作者信息

Guilbaud Théophile, Ewald Jacques, Turrini Olivier, Delpero Jean Robert

机构信息

Théophile Guilbaud, Jacques Ewald, Olivier Turrini, Jean Robert Delpero, Department of Surgery, Institut Paoli Calmettes, 13009 Marseille, France.

出版信息

World J Gastroenterol. 2017 Feb 7;23(5):919-925. doi: 10.3748/wjg.v23.i5.919.

DOI:10.3748/wjg.v23.i5.919
PMID:28223737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5296209/
Abstract

In patients undergoing pancreaticoduodenectomy (PD), unrecognized hemodynamically significant celiac axis (CA) stenosis impairs hepatic arterial flow by suppressing the collateral pathways supplying arterial flow from the superior mesenteric artery and leads to serious hepatobiliary complications due to liver and biliary ischemia, with a high rate of mortality. CA stenosis is usually due to an extrinsic compression by a previously asymptomatic median arcuate ligament (MAL). MAL is diagnosed by computerized tomography in about 10% of the candidates for PD, but only half are found to be hemodynamically significant during the gastroduodenal artery clamping test with Doppler assessment, which is mandatory before any resection. MAL release is usually efficient to restore an adequate liver blood inflow and prevent ischemic complications. In cases of failure in MAL release, postponed PD with secondary stenting of the CA and reoperation for PD should be considered as an alternative to immediate hepatic artery reconstruction, which involves the risk of postoperative thrombosis of the arterial reconstruction. We recently used this two-stage strategy in a patient undergoing surgery for pancreatic adenocarcinoma.

摘要

在接受胰十二指肠切除术(PD)的患者中,未被识别的具有血流动力学意义的腹腔干(CA)狭窄会抑制从肠系膜上动脉供应动脉血流的侧支通路,从而损害肝动脉血流,并由于肝脏和胆道缺血导致严重的肝胆并发症,死亡率很高。CA狭窄通常是由先前无症状的正中弓状韧带(MAL)外部压迫所致。在约10%的PD候选患者中,通过计算机断层扫描诊断出MAL,但在使用多普勒评估的胃十二指肠动脉夹闭试验中,只有一半被发现具有血流动力学意义,而该试验在任何切除术前都是必需的。MAL松解通常能有效恢复足够的肝脏血流并预防缺血性并发症。在MAL松解失败的情况下,应考虑延期PD并对CA进行二期支架置入,然后再次进行PD手术,作为直接肝动脉重建的替代方案,因为直接肝动脉重建存在术后动脉重建血栓形成的风险。我们最近在一名接受胰腺腺癌手术的患者中采用了这种两阶段策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bf9/5296209/552735fb6dd9/WJG-23-919-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bf9/5296209/1be3704cd377/WJG-23-919-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bf9/5296209/ca04734f7034/WJG-23-919-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bf9/5296209/75d0dc6c16b9/WJG-23-919-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bf9/5296209/552735fb6dd9/WJG-23-919-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bf9/5296209/1be3704cd377/WJG-23-919-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bf9/5296209/ca04734f7034/WJG-23-919-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bf9/5296209/75d0dc6c16b9/WJG-23-919-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bf9/5296209/552735fb6dd9/WJG-23-919-g004.jpg

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Eur J Surg Oncol. 2016 May;42(5):616-24. doi: 10.1016/j.ejso.2016.02.003. Epub 2016 Feb 13.
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Contemporary management of median arcuate ligament syndrome provides early symptom improvement.
胰十二指肠切除术中合并腹腔干狭窄的胰头癌治疗策略:一例病例报告及文献复习
World J Gastroenterol. 2022 Feb 28;28(8):868-877. doi: 10.3748/wjg.v28.i8.868.
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Two-way Revascularization to Manage Celiac Artery Stenosis during Pancreaticoduodenectomy: A Case Report.胰十二指肠切除术中采用双向血运重建治疗腹腔干狭窄:一例报告
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Aneurysms of Pancreaticoduodenal Artery due to Median Arcuate Ligament Syndrome, Treated by Open Surgery and Laparoscopic Surgery.经开放手术和腹腔镜手术治疗的正中弓状韧带综合征所致胰十二指肠动脉瘤
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