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肛周克罗恩病:挑战与解决方案

Perianal Crohn's disease: challenges and solutions.

作者信息

Kelley Katherine A, Kaur Taranjeet, Tsikitis Vassiliki L

机构信息

Department of General Surgery, Division of Gastrointestinal and General Surgery, Oregon Health and Sciences University, Portland, OR, USA.

出版信息

Clin Exp Gastroenterol. 2017 Feb 8;10:39-46. doi: 10.2147/CEG.S108513. eCollection 2017.

DOI:10.2147/CEG.S108513
PMID:28223835
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5308478/
Abstract

Perianal Crohn's disease affects a significant number of patients with Crohn's disease and is associated with poor quality of life. The nature of the disease, compounded by presentation of various disease severities, has made the treatment of perianal Crohn's disease difficult. The field continues to evolve with the use of both historical and contemporary solutions to address the challenges associated with it. The goal of this article is to review current literature regarding medical and surgical treatment, as well as the future directions of therapy.

摘要

肛周克罗恩病影响着大量克罗恩病患者,且与生活质量差相关。该疾病的性质,再加上各种疾病严重程度的表现,使得肛周克罗恩病的治疗变得困难。随着历史和当代解决方案的应用以应对与之相关的挑战,该领域不断发展。本文的目的是综述有关药物和手术治疗的当前文献,以及治疗的未来方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05a7/5308478/c85d3dc5dade/ceg-10-039Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05a7/5308478/c85d3dc5dade/ceg-10-039Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05a7/5308478/c85d3dc5dade/ceg-10-039Fig1.jpg

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Surgical management of fistulating perianal Crohn's disease: a UK survey.肛瘘性肛周克罗恩病的外科治疗:一项英国调查。
Colorectal Dis. 2017 Mar;19(3):266-273. doi: 10.1111/codi.13462.
2
Combined Medical and Surgical Approach Improves Healing of Septic Perianal Crohn's Disease.内科与外科联合治疗方法可改善肛周化脓性克罗恩病的愈合情况。
J Am Coll Surg. 2016 Sep;223(3):506-514.e1. doi: 10.1016/j.jamcollsurg.2016.05.017. Epub 2016 Jun 5.
3
Ligation of the intersphincteric fistula tract for the treatment of fistula-in-ano: experience of a tertiary care centre in South India.
肛周瘘管患者克罗恩病的早期诊断:系统评价及肛周警示指标的制定
Tech Coloproctol. 2025 Mar 28;29(1):89. doi: 10.1007/s10151-024-03106-y.
4
Observational Burden of Illness Study in Patients With Crohn's Disease With and Without Perianal Fistulas in the United States.美国克罗恩病伴和不伴肛周瘘患者的疾病负担观察性研究
Gastro Hep Adv. 2023 Aug 24;2(8):1066-1076. doi: 10.1016/j.gastha.2023.08.011. eCollection 2023.
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Exploring Health-Related Quality of Life in Patients with Anal Fistulas: A Comprehensive Study.肛瘘患者健康相关生活质量的探索:一项综合研究。
Life (Basel). 2023 Oct 3;13(10):2008. doi: 10.3390/life13102008.
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[Perianal Fistula: An Overview].[肛周瘘管:概述]
J Korean Soc Radiol. 2023 May;84(3):565-585. doi: 10.3348/jksr.2023.0018. Epub 2023 May 30.
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Perianal fistulizing Crohn's disease is associated with a higher prevalence of HPV in the anorectal fistula tract. A comparative study.肛旁瘘管型克罗恩病与肛门直肠瘘管中 HPV 的更高患病率相关。一项对照研究。
Clinics (Sao Paulo). 2023 May 29;78:100219. doi: 10.1016/j.clinsp.2023.100219. eCollection 2023.
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