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埃博拉病毒病治疗进展

Updates on Treatment of Ebola Virus Disease.

作者信息

Krishnasamy Lakshmi, Saikumar Chitralekha

机构信息

Department of Microbiology, Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai, Tamil Nadu, 600044, India.

Department of Microbiology, Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai, Tamil nadu, 600044, India.

出版信息

Malays J Med Sci. 2015 Nov;22(6):54-57.

PMID:28223886
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5295760/
Abstract

Ebola viral disease is one of the major threats world wide. But the treatment option is merely supportive and symptomatic therapy. Vaccination and drug therapies are still under trial. This article throws light into the various emerging treatment options for the Ebola viral disease.

摘要

埃博拉病毒病是全球主要威胁之一。但其治疗方法仅为支持性和对症治疗。疫苗接种和药物治疗仍在试验中。本文介绍了埃博拉病毒病的各种新兴治疗方法。

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Updates on Treatment of Ebola Virus Disease.埃博拉病毒病治疗进展
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引用本文的文献

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本文引用的文献

1
Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe.重组水疱性口炎病毒埃博拉疫苗在非洲和欧洲的1期试验
N Engl J Med. 2016 Apr 28;374(17):1647-60. doi: 10.1056/NEJMoa1502924. Epub 2015 Apr 1.
2
Favipiravir for children with Ebola.法匹拉韦用于患有埃博拉的儿童。
Lancet. 2015 Feb 14;385(9968):603-604. doi: 10.1016/S0140-6736(15)60232-X.
3
Treatment of Ebola virus infection with antibodies from reconvalescent donors.使用康复者捐献者的抗体治疗埃博拉病毒感染。
Emerg Infect Dis. 2015 Mar;21(3):521-3. doi: 10.3201/eid2103.141838.
4
Ebola vaccine--an urgent international priority.埃博拉疫苗——一项紧迫的国际优先事项。
N Engl J Med. 2014 Dec 11;371(24):2249-51. doi: 10.1056/NEJMp1412166. Epub 2014 Oct 7.
5
Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge.黑猩猩腺病毒疫苗可产生针对埃博拉病毒挑战的急性和持久保护免疫。
Nat Med. 2014 Oct;20(10):1126-9. doi: 10.1038/nm.3702. Epub 2014 Sep 7.
6
Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp.ZMapp 逆转非人灵长类动物的晚期埃博拉病毒病。
Nature. 2014 Oct 2;514(7520):47-53. doi: 10.1038/nature13777. Epub 2014 Aug 29.
7
A practical treatment for patients with Ebola virus disease.埃博拉病毒病患者的一种实用治疗方法。
J Infect Dis. 2015 Feb 15;211(4):661-2. doi: 10.1093/infdis/jiu474. Epub 2014 Aug 25.
8
Development of CMX001 (Brincidofovir) for the treatment of serious diseases or conditions caused by dsDNA viruses.开发CMX001(布林西多福韦)用于治疗由双链DNA病毒引起的严重疾病或病症。
Expert Rev Anti Infect Ther. 2014 Oct;12(10):1171-8. doi: 10.1586/14787210.2014.948847. Epub 2014 Aug 13.
9
The clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry.临床批准的药物胺碘酮、决奈达隆和维拉帕米可抑制丝状病毒进入细胞。
J Antimicrob Chemother. 2014 Aug;69(8):2123-31. doi: 10.1093/jac/dku091. Epub 2014 Apr 7.
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Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430.新型广谱核苷类似物 BCX4430 对丝状病毒病的防护作用。
Nature. 2014 Apr 17;508(7496):402-5. doi: 10.1038/nature13027. Epub 2014 Mar 2.