Chan Kin Wai Edwin, Lee Kim Hung, Wong Hei Yi Vicky, Tsui Siu Yan Bess, Wong Yuen Shan, Pang Kit Yi Kristine, Mou Jennifer Wai Cheung, Tam Yuk Him
Kin Wai Edwin Chan, Kim Hung Lee, Hei Yi Vicky Wong, Siu Yan Bess Tsui, Yuen Shan Wong, Kit Yi Kristine Pang, Jennifer Wai Cheung Mou, Yuk Him Tam, Division of Paediatric Surgery and Paediatric Urology, Department of Surgery, the Prince of Wales Hospital, the Chinese University of Hong Kong, Hong Kong, China.
World J Clin Pediatr. 2017 Feb 8;6(1):40-44. doi: 10.5409/wjcp.v6.i1.40.
To compare the outcome between patients with jejunoileal atresia (JIA) associated with cystic meconium peritonitis (CMP) and patients with isolated JIA (JIA without CMP).
A retrospective study was conducted for all neonates with JIA operated in our institute from January 2005 to January 2016. Demographics including the gestation age, sex, birth weight, age at operation, the presence of associated syndrome was recorded. Clinical outcome including the type of operation performed, operative time, the need for reoperation and mortality were studied. The demographics and the outcome between the 2 groups were compared.
During the study period, 53 neonates had JIA underwent operation in our institute. Seventeen neonates (32%) were associated with CMP. There was no statistical difference on the demographics in the two groups. Patients with CMP had earlier operation than patients with isolated JIA (mean 1.4 d 3 d, = 0.038). Primary anastomosis was performed in 16 patients (94%) with CMP and 30 patients (83%) with isolated JIA ( = 0.269). Patients with CMP had longer operation (mean 190 min 154 min, = 0.004). There were no statistical difference the need for reoperation (3 6, = 0.606) and mortality (2 1, = 0.269) between the two groups.
Primary intestinal anastomosis can be performed in 94% of patients with JIA associated with CMP. Although patients with CMP had longer operative time, the mortality and reoperation rates were low and were comparable to patients with isolated JIA.
比较空回肠闭锁(JIA)合并胎粪性腹膜炎(CMP)的患儿与单纯空回肠闭锁(不合并CMP的JIA)患儿的治疗结果。
对2005年1月至2016年1月在我院接受手术的所有空回肠闭锁新生儿进行回顾性研究。记录人口统计学资料,包括胎龄、性别、出生体重、手术年龄、是否存在相关综合征。研究临床结果,包括手术类型、手术时间、再次手术需求和死亡率。比较两组的人口统计学资料和治疗结果。
在研究期间,53例空回肠闭锁新生儿在我院接受了手术。17例新生儿(32%)合并胎粪性腹膜炎。两组在人口统计学资料上无统计学差异。合并胎粪性腹膜炎的患儿比单纯空回肠闭锁的患儿手术时间更早(平均1.4天对3天,P = 0.038)。16例(94%)合并胎粪性腹膜炎的患儿和30例(83%)单纯空回肠闭锁的患儿进行了一期吻合(P = 0.269)。合并胎粪性腹膜炎的患儿手术时间更长(平均190分钟对154分钟,P = 0.004)。两组在再次手术需求(3对6,P = 0.606)和死亡率(2对1,P = 0.269)方面无统计学差异。
94%的空回肠闭锁合并胎粪性腹膜炎的患儿可进行一期肠吻合。虽然合并胎粪性腹膜炎的患儿手术时间更长,但死亡率和再次手术率较低,与单纯空回肠闭锁的患儿相当。