Nawai Ampicha, Leveille Suzanne G, Shmerling Robert H, van der Leeuw Guusje, Bean Jonathan F
College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA, USA.
Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Aging Clin Exp Res. 2017 Dec;29(6):1139-1147. doi: 10.1007/s40520-016-0700-9. Epub 2017 Feb 21.
Concerns about polypharmacy and medication side effects contribute to undertreatment of geriatric pain. This study examines use and effects of pharmacologic treatment for persistent pain in older adults.
The MOBILIZE Boston Study included 765 adults aged ≥70 years, living in the Boston area, recruited from 2005 to 2008. We studied 599 participants who reported chronic pain at baseline. Pain severity, measured using the Brief Pain Inventory (BPI) severity subscale, was grouped as very mild (BPI <2), mild (BPI 2-3.99), and moderate to severe (BPI 4-10). Medications taken in the previous 2 weeks were recorded from medication bottles in the home interview.
Half of participants reported using analgesic medications in the previous 2 weeks. Older adults with moderate to severe pain were more likely to use one or more analgesic medications daily than those with very mild pain (49 versus 11%, respectively). The most commonly used analgesic was acetaminophen (28%). Opioid analgesics were used daily by 5% of participants. Adjusted for health and demographic factors, pain severity was strongly associated with daily analgesic use (moderate-severe pain compared to very mild pain, adj. OR 7.19, 95% CI 4.02-12.9). Nearly one third of participants (30%) with moderate to severe pain felt they needed a stronger pain medication while 16% of this group were concerned they were using too much pain medication.
Serious gaps persist in pain management particularly for older adults with the most severe chronic pain. Greater efforts are needed to understand barriers to effective pain management and self-management in the older population.
对多重用药和药物副作用的担忧导致老年疼痛治疗不足。本研究探讨了老年人持续性疼痛的药物治疗使用情况及效果。
“波士顿老年纵向研究”纳入了2005年至2008年从波士顿地区招募的765名年龄≥70岁的成年人。我们研究了599名在基线时报告有慢性疼痛的参与者。使用简明疼痛量表(BPI)严重程度子量表测量的疼痛严重程度分为非常轻微(BPI<2)、轻微(BPI 2 - 3.99)和中度至重度(BPI 4 - 10)。在家庭访谈中,从药瓶记录前两周服用的药物。
一半的参与者报告在前两周使用了止痛药物。中度至重度疼痛的老年人比非常轻微疼痛的老年人更有可能每天使用一种或多种止痛药物(分别为49%和11%)。最常用的止痛药物是对乙酰氨基酚(28%)。5%的参与者每天使用阿片类止痛药物。经健康和人口统计学因素调整后,疼痛严重程度与每日止痛药物使用密切相关(中度至重度疼痛与非常轻微疼痛相比,调整后的比值比为7.19,95%置信区间为4.02 - 12.9)。近三分之一(30%)中度至重度疼痛的参与者认为他们需要更强效的止痛药物,而该组中有16%的人担心他们使用的止痛药物过多。
疼痛管理方面仍存在严重差距,尤其是对于患有最严重慢性疼痛的老年人。需要做出更大努力来了解老年人群有效疼痛管理和自我管理的障碍。