Daltro Luise Ribeiro, Yaegashi Lygia Bertalha, Freitas Rodrigo Abdalah, Fantini Bruno de Carvalho, Souza Cacilda da Silva
Division of Dermatology, Internal Medicine Department - Medical School of Ribeirão Preto - Universidade de São Paulo- Ribeirão Preto (SP) -Brazil.
Department of Pathology - Medical School of Ribeirão Preto - Universidade de São Paulo- Ribeirão Preto (SP) -Brazil.
An Bras Dermatol. 2017 Jan-Feb;92(1):110-112. doi: 10.1590/abd1806-4841.20174502.
Blue nevus is a benign melanocytic lesion whose most frequent variants are dendritic (common) blue nevus and cellular blue nevus. Atypical cellular blue nevus presents an intermediate histopathology between the typical and a rare variant of malignant blue nevus/melanoma arising in a cellular blue nevus. An 8-year-old child presented a pigmented lesion in the buttock since birth, but with progressive growth in the last two years. After surgical excision, histopathological examination revealed atypical cellular blue nevus. Presence of mitoses, ulceration, infiltration, cytological atypia or necrosis may occur in atypical cellular blue nevus, making it difficult to differentiate it from melanoma. The growth of blue nevus is unusual and considered of high-risk for malignancy, being an indicator for complete resection and periodic follow-up of these patients.
蓝色痣是一种良性黑素细胞病变，其最常见的变体是树枝状（普通）蓝色痣和细胞性蓝色痣。非典型细胞性蓝色痣在组织病理学上介于典型的细胞性蓝色痣和细胞性蓝色痣中罕见的恶性蓝色痣/黑色素瘤变体之间。一名8岁儿童自出生以来臀部就有一个色素沉着病变，但在过去两年中逐渐增大。手术切除后，组织病理学检查显示为非典型细胞性蓝色痣。非典型细胞性蓝色痣可能出现有丝分裂、溃疡、浸润、细胞异型性或坏死，这使得它难以与黑色素瘤区分开来。蓝色痣的生长情况不寻常，被认为具有高恶性风险，是这些患者进行完整切除和定期随访的一个指标。
