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黎巴嫩患者和药剂师对非专利药替代的认知与行为

Perceptions and behaviors of patients and pharmacists towards generic drug substitution in Lebanon.

作者信息

Saleh Shadi, Abou Samra Clara, Jleilaty Stewart, Constantin Joanne, El Arnaout Nour, Dimassi Hani, Al-Bittar Dania

机构信息

Department of Health Management and Policy, Faculty of Health Sciences, American University of Beirut, Riad El Solh, Beirut, 1107 2020, Lebanon.

School of Pharmacy, Lebanese American University, Beirut, Lebanon.

出版信息

Int J Clin Pharm. 2017 Oct;39(5):1101-1109. doi: 10.1007/s11096-017-0509-4. Epub 2017 Aug 19.

Abstract

Background Patients, physicians and pharmacists are key stakeholders in the implementation of generic substitution policies. Objectives To explore Lebanese patients' perceptions and experience, and pharmacists' dispensing patterns towards the newly enacted unified health prescription policy promoting generic substitution. Setting Pharmacies in Beirut, the capital of Lebanon. Methods A cross-sectional design employing self-administered questionnaires to survey a total of 128 patients and 25 pharmacists. Chi square test and multiple logistic regression were performed. Main outcome Perceptions and behaviors of patients and pharmacists towards the unified health prescription and generic substitution. Results Fourty-eight percent of the patients knew the definition of generic drugs, among which 59.0% perceived that generic drugs have the same effectiveness as their branded alternatives and 59.0% perceiving that generic drugs could reduce Lebanon's medical bill as well. Sixty-one percent of the patients were aware of the unified health prescription. Only 13.6% of the pharmacists suggested to patients to replace prescribed brand drug by a generic when their prescriptions were not marked with non-substitution. Conclusions Progress has been made with regards to enhancing generic substitution in the Lebanese healthcare field. However, it remains important to educate patients about generic medicines and plan context-specific schemes that promote prescribing and dispensing of generic drugs among physicians and pharmacists.

摘要

背景

患者、医生和药剂师是实施通用名药物替代政策的关键利益相关者。目的:探讨黎巴嫩患者对新颁布的促进通用名药物替代的统一健康处方政策的看法和体验,以及药剂师的配药模式。地点:黎巴嫩首都贝鲁特的药店。方法:采用横断面设计,通过自填问卷对128名患者和25名药剂师进行调查。进行卡方检验和多元逻辑回归分析。主要结果:患者和药剂师对统一健康处方和通用名药物替代的看法及行为。结果:48%的患者知道通用名药物的定义,其中59.0%的患者认为通用名药物与其品牌替代药物具有相同的疗效,59.0%的患者还认为通用名药物可以降低黎巴嫩的医疗费用。61%的患者知晓统一健康处方。当处方未标明不可替代时,只有13.6%的药剂师建议患者用通用名药物替代处方中的品牌药物。结论:黎巴嫩医疗领域在加强通用名药物替代方面取得了进展。然而,对患者进行通用名药物教育以及制定针对具体情况的方案以促进医生和药剂师开具和配发通用名药物仍然很重要。

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