硫代苹果酸金钠对感染披膜病毒和黄病毒的成年瑞士/A2G小鼠的影响。
The effect of gold sodium thiomalate in adult Swiss/A2G mice infected with togaviruses and flaviviruses.
作者信息
Mehta S, Webb H E
机构信息
Neurovirology Unit, Rayne Institute, London, U.K.
出版信息
J Gen Virol. 1987 Oct;68 ( Pt 10):2665-8. doi: 10.1099/0022-1317-68-10-2665.
PMID:2822844
Abstract
Treatment of adult mice with gold sodium thiomalate made the normally non-lethal Semliki Forest virus and Sindbis virus infections lethal and increased the virulence of Langat and West Nile viruses. These changes were associated with an enhanced virus invasion of the brain. Depression of the humoral antibody response was not observed.
摘要
用硫代苹果酸钠金处理成年小鼠，会使通常无致死性的塞姆利基森林病毒和辛德毕斯病毒感染变得具有致死性，并增强兰加特病毒和西尼罗河病毒的毒力。这些变化与病毒对大脑的侵袭增强有关。未观察到体液抗体反应受到抑制。
相似文献
1
The effect of gold sodium thiomalate in adult Swiss/A2G mice infected with togaviruses and flaviviruses.硫代苹果酸金钠对感染披膜病毒和黄病毒的成年瑞士/A2G小鼠的影响。
J Gen Virol. 1987 Oct;68 ( Pt 10):2665-8. doi: 10.1099/0022-1317-68-10-2665.
2
The effect of gold sodium thiomalate and its constituent part, thiomalate, on the virus titres and the lysosomal enzyme activity in peritoneal macrophages of Swiss/A2G mice infected with the avirulent strain of Semliki Forest virus.硫代苹果酸金钠及其组成部分硫代苹果酸对感染了无毒力塞姆利基森林病毒株的瑞士/A2G小鼠腹腔巨噬细胞中病毒滴度和溶酶体酶活性的影响。
J Exp Pathol (Oxford). 1990 Jun;71(3):359-66.
3
Modulation of a systemic Semliki Forest virus infection in mice by defective interfering virus.缺陷干扰病毒对小鼠全身性Semliki森林病毒感染的调节作用
J Gen Virol. 1984 Oct;65 ( Pt 10):1827-31. doi: 10.1099/0022-1317-65-10-1827.
4
Induction of membrane proliferation in mouse CNS by gold sodium thiomalate with reference to increased virulence of the avirulent Semliki Forest virus.硫代苹果酸金钠对小鼠中枢神经系统膜增殖的诱导作用及其与无毒力的Semliki森林病毒毒力增强的关系
Biosci Rep. 1990 Jun;10(3):271-9. doi: 10.1007/BF01117243.
5
Lysosomal enzyme changes in macrophages from mice given myocrisin and infected with avirulent Semliki Forest virus.给予金诺芬并感染无毒力的Semliki森林病毒的小鼠巨噬细胞中溶酶体酶的变化。
Br J Exp Pathol. 1982 Aug;63(4):443-6.
6
Further studies of macrophages in relationship to avirulent Semliki Forest virus infections.关于无毒力的Semliki森林病毒感染与巨噬细胞关系的进一步研究。
Br J Exp Pathol. 1980 Apr;61(2):150-5.
7
Cross-infection enhancement among African flaviviruses by immune mouse ascitic fluids.
Cytobios. 1987;49(196):49-55.
8
Modifications by sodium auro-thio-malate of the expression of virulence in mice by defined strains of Semliki Forest virus.金硫代苹果酸钠对特定株塞姆利基森林病毒在小鼠体内毒力表达的修饰作用
J Gen Virol. 1974 Jul;24(1):221-8. doi: 10.1099/0022-1317-24-1-221.
9
10
CNS pathogenesis following a dual viral infection with Semliki Forest (alphavirus) and Langat (flavivirus).塞姆利基森林病毒（甲病毒属）和兰加特病毒（黄病毒属）双重病毒感染后的中枢神经系统发病机制。
Br J Exp Pathol. 1988 Apr;69(2):197-208.
引用本文的文献
1
CNS pathogenesis following a dual viral infection with Semliki Forest (alphavirus) and Langat (flavivirus).塞姆利基森林病毒（甲病毒属）和兰加特病毒（黄病毒属）双重病毒感染后的中枢神经系统发病机制。
Br J Exp Pathol. 1988 Apr;69(2):197-208.
2
The effect of gold sodium thiomalate and its constituent part, thiomalate, on the virus titres and the lysosomal enzyme activity in peritoneal macrophages of Swiss/A2G mice infected with the avirulent strain of Semliki Forest virus.硫代苹果酸金钠及其组成部分硫代苹果酸对感染了无毒力塞姆利基森林病毒株的瑞士/A2G小鼠腹腔巨噬细胞中病毒滴度和溶酶体酶活性的影响。
J Exp Pathol (Oxford). 1990 Jun;71(3):359-66.
Zotero 插件