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遗传性多发性骨软骨瘤患者的骨软骨瘤与脊髓压迫:一例报告

Osteochondroma and Spinal Cord Compression in a Patient With Hereditary Multiple Exostoses: A Case Report.

作者信息

Zoboski Robert J

机构信息

Private Practice, Summit, IL.

出版信息

J Chiropr Med. 2017 Mar;16(1):72-77. doi: 10.1016/j.jcm.2016.10.007. Epub 2016 Dec 12.

Abstract

OBJECTIVE

The purpose of this report was to describe the presentation of a patient with hereditary multiple exostoses and thoracic spinal cord compression from an osteochondroma.

CLINICAL FEATURES

A 31-year-old female presented to a chiropractic clinic with a history of hereditary multiple exostoses and back pain that had existed since the age of 16 years. She had a past medical history that was remarkable for 3 prior surgeries for mass removal. Examination revealed a left upper midscapular mass with decreased sensation.

INTERVENTION/OUTCOME: Magnetic resonance imaging, computed tomography, and biopsy led to a diagnosis of osteochondroma. These diagnostic modalities confirmed that there was no malignant degeneration. Initial magnetic resonance imaging revealed a large expansive lesion involving the left posterior elements at the region of T3-T4. Subsequent thoracic hemilaminectomy and resection of the spinal tumor with posterior instrumentation and stabilization from T2-T5 resulted in 90% overall subjective improvement.

CONCLUSIONS

A detailed case history, thorough examination, guided advanced imaging, and biopsy provide important information for the diagnosis and appropriate treatment of expansive lesions in patients with hereditary multiple exostoses.

摘要

目的

本报告旨在描述一名患有遗传性多发性骨软骨瘤并因骨软骨瘤导致胸段脊髓受压患者的临床表现。

临床特征

一名31岁女性因遗传性多发性骨软骨瘤病史及自16岁起就存在的背痛就诊于一家整脊诊所。她既往有3次因肿物切除的手术史。体格检查发现左肩胛中部上方有一肿物,伴有感觉减退。

干预措施/结果:磁共振成像、计算机断层扫描及活检确诊为骨软骨瘤。这些诊断方法证实无恶性变。最初的磁共振成像显示T3 - T4区域有一个累及左侧后部结构的巨大膨胀性病变。随后进行了胸段半椎板切除术,并切除了脊髓肿瘤,同时从T2 - T5进行后路内固定和稳定手术,总体主观改善率达90%。

结论

详细的病史、全面的体格检查、有针对性的高级影像学检查及活检为遗传性多发性骨软骨瘤患者膨胀性病变的诊断及恰当治疗提供了重要信息。

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