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全髋关节置换术中的羟基磷灰石。我们使用等离子喷涂多孔钛合金/羟基磷灰石双涂层非骨水泥型股骨柄的经验。

Hydroxyapatite in total hip arthroplasty. Our experience with a plasma spray porous titanium alloy/hydroxyapatite double-coated cementless stem.

作者信息

Castellini Iacopo, Andreani Lorenzo, Parchi Paolo Domenico, Bonicoli Enrico, Piolanti Nicola, Risoli Francesca, Lisanti Michele

机构信息

Orthopaedics and Traumatology 1st Department, University of Pisa, Pisa, Italy.

出版信息

Clin Cases Miner Bone Metab. 2016 Sep-Dec;13(3):221-227. doi: 10.11138/ccmbm/2016.13.3.221. Epub 2017 Feb 10.

Abstract

PURPOSE

Total hip arthroplasty could fail due to many factors and one of the most common is the aseptic loosening. In order to achieve an effective osseointegration and reduce risk of lossening, the use of cemented implant, contact porous bearing surface and organic coating were developed. Aim of this study was to evaluate clinical and radiological mid-term outcomes of a porous titanium alloy/hydroxyapatite double coating manufactured cementless femoral stem applied with "plasma spray" technique and to demonstrate the possibility to use this stem in different types of femoral canals.

METHODS

Between January 2008 and December 2012, 240 consecutive primary total hip arthroplasties (THAs) were performed using a porous titanium alloy/hydroxyapatite double coating manufactured cementless femoral stem. 182 patients were examined: 136 were females (74.7%) and 46 males (25.2%); average age was 72 years old (ranging from 26 to 92 years old). For each patient, Harris Hip Scores (HHS) and Womac Scores were collected. All X-ray images were analyzed in order to demonstrate stem survival rate and subsidence.

RESULTS

Harris Hip Score was good or excellent in 85% of the cases (average 90%) and mean WOMAC score was 97.5 (ranging from 73.4 to 100). No cases of early/late infection or periprosthetic fracture were noticed, with an excellent implant survival rate (100%) in a mean period of 40 months (ranging from 24 and 84 months). 5 cases presented acute implant dislocation, 2 due to wrong cup positioning in a dysplastic acetabulum and 3 after ground level fall. Dorr classification of femoral geometry was uses and the results were: 51 type A bone, 53 type B bone and 78 type C bone. Stem subsidence over 2 mm was considered as a risk factor of future implant loosening and was evidenced in 3 female patients with type C of Dorr classification. No radiolucencies signs around the proximally coated portion of stem or proximal reabsorption were visible during the radiographic follow-up.

CONCLUSIONS

Concerning the use of porous titanium alloy/hydroxyapatite double coating, this study reported an excellent implant survival rate in a mid-term period with a rate of 1,64% of subsidence in patients with type C of femoral canal but with an optimal HHS and Womac Score results. Regarding this stem, primary stability is guaranteed by trapezoid shape of proximal region and tapering in frontal plane through press-fit technique. Radiological absence of pedestal has been accepted as sign of no excessive stress transmission to distal cortex due to its tapered diaphyseal region. Thanks to the reported data, Authors can consider this double coating a valid choice with an excellent medium-term survival and encouraging subsidence results. Further studies are needed to ensure these results can be replicated.

摘要

目的

全髋关节置换术可能因多种因素失败,其中最常见的因素之一是无菌性松动。为了实现有效的骨整合并降低松动风险,人们研发了骨水泥型植入物、接触多孔支承面和有机涂层。本研究的目的是评估采用“等离子喷涂”技术制造的多孔钛合金/羟基磷灰石双涂层非骨水泥型股骨柄的临床和放射学中期结果,并证明在不同类型的股骨髓腔中使用这种股骨柄的可能性。

方法

在2008年1月至2012年12月期间,连续进行了240例初次全髋关节置换术(THA),使用的是多孔钛合金/羟基磷灰石双涂层非骨水泥型股骨柄。对182例患者进行了检查:136例为女性(74.7%),46例为男性(25.2%);平均年龄为72岁(年龄范围为26至92岁)。收集了每位患者的Harris髋关节评分(HHS)和Womac评分。对所有X线图像进行分析,以显示股骨柄生存率和下沉情况。

结果

85%的病例Harris髋关节评分为良好或优秀(平均90%),平均Womac评分为97.5(范围为73.4至100)。未发现早期/晚期感染或假体周围骨折病例,在平均40个月(范围为24至84个月)的时间内,植入物生存率极佳(100%)。5例出现急性植入物脱位,2例是由于发育不良髋臼中髋臼杯位置错误,3例是在平地跌倒后发生。采用Dorr股骨几何分类法,结果为:51例A型骨,53例B型骨和78例C型骨。超过2mm的股骨柄下沉被视为未来植入物松动的危险因素,在3例Dorr分类为C型的女性患者中得到证实。在放射学随访期间,未观察到股骨柄近端涂层部分周围的透光线状迹象或近端吸收。

结论

关于多孔钛合金/羟基磷灰石双涂层的使用,本研究报告了中期极佳的植入物生存率,股骨髓腔C型患者的下沉率为1.64%,但HHS和Womac评分结果最佳。对于这种股骨柄,近端区域的梯形形状和通过压配技术在额平面上的逐渐变细保证了初始稳定性。由于其骨干逐渐变细的区域,放射学上无骨桥被认为是没有过度应力传递至远端皮质的迹象。基于所报告的数据,作者认为这种双涂层是一个有效的选择,具有极佳的中期生存率和令人鼓舞的下沉结果。需要进一步研究以确保这些结果能够被复制。

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