Krčová I, Stanislavová M, Peško K, Furdová A, Koller J
Cesk Slov Oftalmol. 2016 Winter;72(6):204-208.
Amniotic membrane is the innermost part of the fetal and packaging for its exceptional qualities likes to be used in treating many ocular pathologies. Amniotic membrane has improved the ability to treat ocular surface disease. It has unique features like support conjunctival and corneal epithelialization.
Retrospective analysis of group patients who underwent amniotic membrane transplantation at the Department of Ophthalmology Faculty of Medicine and UN Bratislava in 2013-2015. We evaluated indications amniotic membrane transplantation, the percentage, the number of transplants and the number of failures and retransplantation of the membrane.
In group of 71 patients (amniotic membrane covering defects of conjunctiva and cornea) male patients formed a slight predominance of males in the number of patients a slightly larger preponderance in 38 women (53.5 %) - 52 surgeries (59.09 %) and 33 male (46.5 %) in 36 interventions (40.91 %). The left eye was affected in 40 interventions (45.45 %), 48 interventions were on the right eye (54.54 %). The most common cause application of 30.68 % in 27 eyes was corneal ulcer, bullous keratopathy followed by the 11.36 % in 10 eyes, and the ulcer herpetic keratitis in 9.10 % in 8 eyes. Injury or vulnus penetrans 6.82 % in 6 eyes, ulcers caused by paresis n. facialis 6.82 % in 6 eyes and sicca syndrome 5.68 % in 5 eyes.In 2015 we applied amniotic membrane covering the defect of eyelids after trauma in one patient.
Amniotic membrane is the appropriate treatment in a number of diseases of ocular surface when conservative methods of treatment fail. In corneal application can prevent the execution of more aggressive treatment, such as keratoplasty, or to soothe inflammation and keratoplasty is not performed as emergent, but elective.Key words: amniotic membrane transplantation, eye diseases.
羊膜是胎儿最内层的膜，因其具有诸多特殊性质，常被用于治疗多种眼部疾病。羊膜改善了治疗眼表疾病的能力。它具有独特的特性，如支持结膜和角膜上皮化。
对2013 - 2015年在布拉迪斯拉发医科大学眼科接受羊膜移植的患者组进行回顾性分析。我们评估了羊膜移植的适应证、移植百分比、移植数量以及膜的失败和再次移植数量。
在71例患者（羊膜覆盖结膜和角膜缺损）组中，男性患者在患者数量上略占优势，38名女性（53.5%）进行了52次手术（59.09%），33名男性（46.5%）进行了36次干预（40.91%）。40次干预（45.45%）累及左眼，48次干预（54.54%）累及右眼。最常见的应用原因是27只眼中30.68%为角膜溃疡，其次是10只眼中11.36%为大疱性角膜病变，8只眼中9.10%为疱疹性角膜溃疡。6只眼中6.82%为穿透性损伤或外伤，6只眼中6.82%为面神经麻痹引起的溃疡，5只眼中5.68%为干燥综合征。2015年，我们对1例外伤后眼睑缺损患者应用了羊膜覆盖。
当保守治疗方法失败时，羊膜是许多眼表疾病的合适治疗方法。在角膜应用中，它可以防止进行更激进的治疗，如角膜移植术，或缓解炎症，使角膜移植术不是作为急诊进行，而是择期进行。关键词：羊膜移植，眼部疾病。
