Kitahara S, Murakuni H, Kudo M, Waki K, Hayashi A, Suzuki T, Tsugu Y
2nd Dept. of Surgery & Pathology, Toho Univ. School of Med.
Gan No Rinsho. 1987 Sep;33(11):1379-84.
This report deals with a histologic demonstration of a combined tumor of early signet ring cell carcinoma and lymphoma of the stomach in a 52-year-old Japanese man. The Gastric carcinoma was found by a systemic work up for a tonsillar lymphoma. The relationship between the malignant lymphomas of the stomach and of the tonsil is not clear in this case. The carcinoma and lymphoma of the stomach were both small, and the depth of invasion was localized to the mucosa and submucosa, respectively. The lymphoma was observed just beneath the cancer and was a diffuse, large cell type, and of the same histologic typing as the tonsillar lymphoma. Based on the broader size of the carcinoma, it is considered that the carcinoma probably induced the lymphoma in the stomach. This of an early combined tumor of carcinoma and lymphoma of the stomach is, to our knowledge, the first to be reported in the literature.
本报告描述了一名52岁日本男性胃早期印戒细胞癌合并淋巴瘤的组织学表现。该胃癌是在对扁桃体淋巴瘤进行全面检查时发现的。此病例中胃淋巴瘤与扁桃体淋巴瘤之间的关系尚不清楚。胃的癌和淋巴瘤均较小,浸润深度分别局限于黏膜层和黏膜下层。淋巴瘤位于癌灶下方,为弥漫性大细胞型,组织学类型与扁桃体淋巴瘤相同。鉴于癌灶范围更广,推测癌可能诱发了胃内的淋巴瘤。据我们所知,这种胃早期癌合并淋巴瘤的病例是文献中首次报道。