Nakagawa K, Sakaki S, Fujita H, Matsuoka K, Nishimura K, Tsunekawa K
Gan No Rinsho. 1987 Jul;33(8):937-42.
A case of synchronous multiple primary neoplasms, an intracranial malignant lymphoma and a gastric carcinoma, is presented. A 63-year-old man was admitted to our hospital with complaints of dizziness and a floating sensation on gait. A CT scan after admission, revealed a well-defined, nodular high density area in the left frontal lobe, which was markedly enhanced by the contrast medium. In order to rule out a metastatic brain tumor, examinations were performed as a consequence, and, the gastric carcinoma was found. A partial removal of the brain tumor and a gastrectomy were performed in two stages. Pathologically, the diagnosis of the brain tumor indicated a malignant lymphoma of large cell type, and that of the gastric carcinoma was an adenocarcinoma. The patient received postoperative irradiation and chemotherapy and was discharged in a good condition. He died of pneumonia 21 months after the operation. Necropsy revealed a marked atrophy of the brain without recurrence of the malignant lymphoma and no recurrence of a gastric cancer.
本文报告一例同步发生的多原发性肿瘤,即颅内恶性淋巴瘤和胃癌。一名63岁男性因头晕和步态飘浮感入院。入院后CT扫描显示左额叶有一个边界清晰的结节状高密度区,造影剂明显增强。为排除脑转移瘤,随后进行了检查,发现了胃癌。分两阶段进行了脑肿瘤部分切除和胃切除术。病理检查显示,脑肿瘤诊断为大细胞型恶性淋巴瘤,胃癌诊断为腺癌。患者接受了术后放疗和化疗,出院时情况良好。术后21个月死于肺炎。尸检显示脑明显萎缩,恶性淋巴瘤未复发,胃癌也未复发。