Hematology Research Center, Department of Hematology, Medical Oncology and Stem Cell Transplantation, Shiraz University of Medical Sciences, Shiraz, Iran.
Associate Professor of Endocrinology & Metabolism Department of Internal Medicine, Endocrine and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Cancer Rep (Hoboken). 2024 Jun;7(6):e2113. doi: 10.1002/cnr2.2113.
Renal cell carcinoma (RCC) is one of the most common and prevalent cancers all around the world with a prevalence of 3%. Approximately twenty percent of patients present with metastasis at the time of diagnosis, while late metastasis in renal cell carcinoma is a quite familiar phenomenon. Head and neck and particularly thyroid metastasis from RCC are rare events.
We present a case of a 75-year-old woman who developed thyroid nodules 13 years after nephrectomy for RCC. Diagnosis confirmed metastatic RCC through clinical history, histomorphology, and immunohistochemistry. Imaging studies revealed thyroid lesions without metastasis in other organs. The patient underwent total thyroidectomy and remains symptom-free after 2 years of follow-up.
This case highlights the importance of considering metastatic lesions is crucial in managing thyroid nodules in patients with a history of cancer, particularly RCC.
肾细胞癌（RCC）是全世界最常见和普遍的癌症之一，患病率为 3%。大约 20%的患者在诊断时已出现转移，而肾细胞癌的晚期转移是一种相当常见的现象。头颈部，特别是 RCC 甲状腺转移较为罕见。
我们报告了一例 75 岁女性患者，在因 RCC 行肾切除术 13 年后出现甲状腺结节。通过临床病史、组织形态学和免疫组织化学检查诊断为转移性 RCC。影像学研究显示甲状腺病变无其他器官转移。患者行甲状腺全切除术，2 年随访后无任何症状。
本病例强调了在管理有癌症病史（特别是 RCC）的患者的甲状腺结节时，考虑转移病变的重要性。
