Hansen L L, Wiecha I, Witschel H
Augenklinik im Klinik um Steglitz der Freien Universität Berlin.
Klin Monbl Augenheilkd. 1987 Aug;191(2):133-6. doi: 10.1055/s-2008-1050482.
The authors report on two patients who presented with sudden loss of vision, due to irodocyclitis and retinochoroiditis in one patient and optic neuritis in the other. AIDS was diagnosed in both patients on the basis of a positive HIV antibody assay, lymphopenia, and a reduced helper-to-suppressor subset ratio. Soon afterwards, the patient with retinochoroiditis developed the full-blown picture of AIDS with cerebral involvement. Neither anticytomegaly treatment with DHPG nor triple therapy for toxoplasmosis was able to prevent the fatal course. The patient died within six months. In contrast, the patient with optic neuritis recovered full visual acuity. So far there has been no relapse, nor any opportunistic infection in other organs.
作者报告了两名视力突然丧失的患者,其中一名患者因虹膜睫状体炎和视网膜脉络膜炎导致视力丧失,另一名患者则因视神经炎导致视力丧失。两名患者均根据HIV抗体检测呈阳性、淋巴细胞减少以及辅助性T细胞与抑制性T细胞亚群比例降低而被诊断为艾滋病。此后不久,患有视网膜脉络膜炎的患者出现了伴有脑部受累的典型艾滋病症状。无论是使用DHPG进行的抗巨细胞病毒治疗,还是针对弓形虫病的三联疗法,都无法阻止致命病程的发展。该患者在六个月内死亡。相比之下,患有视神经炎的患者视力完全恢复。迄今为止,未出现复发情况,其他器官也未发生任何机会性感染。