Hongtao Zhang, Xuemin Di, Huimin Yu, Zeyang Wang, Lijuan Zhang, Jinxin Zhao, Zezhou Liu, Aixia Sui, Juan Wang
Department of Oncology, The Hebei General Hospital, Shijiazhuang 050051, China.
J Cancer Res Ther. 2016 Dec;12(Supplement):C159-C165. doi: 10.4103/0973-1482.200607.
This study aimed to compare the dose difference in 125 I seed implantation between three-dimensional (3D) print template-guided operation and traditional implantation.
This study retrospectively analyzed 27 patients who underwent 125I seed implantation from August 2015 to December 2015 in Hebei General Hospital. Of these, 13 underwent seed implantation guided by a 3D print template, named the template group, and 14 underwent traditional implantation, named the traditional group. All patients underwent computed tomography (CT) scan. Then, 3D templates were printed in the template group. The implantation was guided by CT and 3D templates. The patients in the traditional group underwent implantation with free hands guided by CT scan. Postplan was performed after the operation. The dose-volume histogram, D90, and V90 were calculated. The D90 values pre- and post-operation were compared in each group. The postoperation V90 values of the two groups were also compared.
The mean D90 values pre- and post-operation in the template group were (87.09 ± 33.63) Gy and (85.31 ± 34.40) Gy, respectively, with no statistically significant difference. The mean D90 values pre- and post-operation in the traditional group were (86.04 ± 29.93) Gy and (74.96 ± 46.10) Gy, respectively, with a statistically significant difference. The mean V90 values postoperation in the template and traditional groups were (92.76% ± 1.89%) and (84.59% ± 7.56%), respectively, with a statistically significant difference.
The postplan and preplan dose parameters of 3D print template-guided seed implantation were nearly consistent. The dose parameters of template group superior to the traditional group. The seeds can be implanted accurately with 3D print template.
本研究旨在比较三维（3D）打印模板引导下的¹²⁵I粒子植入术与传统植入术之间的剂量差异。
本研究回顾性分析了2015年8月至2015年12月在河北医科大学第一医院接受¹²⁵I粒子植入术的27例患者。其中，13例接受3D打印模板引导下的粒子植入术，命名为模板组；14例接受传统植入术，命名为传统组。所有患者均行计算机断层扫描（CT）。然后，模板组打印3D模板。在CT和3D模板引导下进行植入。传统组患者在CT扫描引导下徒手植入。术后进行术后计划。计算剂量体积直方图、D90和V90。比较每组术前和术后的D90值。还比较了两组的术后V90值。
模板组术前和术后的平均D90值分别为（87.09±33.63）Gy和（85.31±34.40）Gy，差异无统计学意义。传统组术前和术后的平均D90值分别为（86.04±29.93）Gy和（74.96±46.10）Gy，差异有统计学意义。模板组和传统组术后的平均V90值分别为（92.76%±1.89%）和（84.59%±7.56%），差异有统计学意义。
3D打印模板引导下粒子植入术的术后计划和术前计划剂量参数基本一致。模板组的剂量参数优于传统组。3D打印模板可准确植入粒子。
