Gao Z, Zhang H T, Wang J, Yu H M, Di X M, Xu K, Liu Z Z, Zhao J X
Department of Oncology, the Hebei General Hospital, Shijiazhuang 050051, China.
Zhonghua Yi Xue Za Zhi. 2019 Dec 17;99(47):3694-3698. doi: 10.3760/cma.j.issn.0376-2491.2019.47.004.
To compare the dose difference of (125)I seeds implantation on superficial metastatic carcinoma between 3D print template guided operation and traditional implantation. To investigate the accuracy of seeds implantation according preplan guided by 3D print template. A total of 21 cases of patient with 27 lesions underwent (125)I seeds implantation from January 2015 to May 2018 in Hebei General Hospital were analyzed retrospectively. In which, ten lesions underwent seeds implantation guided by 3D print template (template group) and 17 lesions underwent free-hand traditional implantation (traditional group). All patients had been fixed as the position of operation and then performed CT scan. After preplan was designed, the 3D templates were printed in template group. Postplan was performed after the operation.The dose volume histogram, D90 was calculated. The D90 pre and post operation were collected and compared in each group. The difference of D90 and the percentage difference of D90 between pre and post operation were calculated by the formula D90d=D90post-D90pre, D90d%=(D90post-D90pre)/D90pre×100%, and compared the difference between two groups. The mean D90 pre and post operation in template group were (92±26) and (93±27) Gy respectively, -0.749, 0.473. The mean D90 pre and post operation in traditional group were (104±29) and (104±26) Gy respectively, -0.139, 0.891. The difference of D90 in two groups were (3.1±2.4) and (10.0±8.7) Gy, -2.5, 0.012. The percentage difference of D90 in two groups were 3.1%±1.9% and 9.5%±7.9%, Compared with the traditional group, the template group had smaller fluctuations, and the difference was statistically significant (-2.7, 0.006) (all 0.05). The dose parameters of 3D template guided seeds implantation between postplan and preplan are nearly consistent.3D template has good repeatability, which provides a theoretical basis for the popularization of 3D printing technology.
比较三维打印模板引导下¹²⁵I粒子植入术与传统植入术治疗浅表转移性癌时粒子植入剂量的差异。探讨三维打印模板引导下粒子植入术按预计划植入的准确性。回顾性分析2015年1月至2018年5月在河北医科大学第一医院行¹²⁵I粒子植入术的21例患者共27个病灶。其中，10个病灶采用三维打印模板引导下粒子植入术（模板组），17个病灶采用徒手传统植入术（传统组）。所有患者均在手术体位固定后行CT扫描。模板组在设计预计划后打印三维模板。术后行后装计划。计算剂量体积直方图、D90。收集并比较每组术前、术后D90。按公式D90d = D90post - D90pre、D90d% = (D90post - D90pre)/D90pre×100%计算两组D90差值及D90术前、术后百分比差值，并比较两组间差异。模板组术前、术后平均D90分别为(92±26) Gy和(93±27) Gy，-0.749，0.473。传统组术前、术后平均D90分别为(104±29) Gy和(104±26) Gy，-0.139，0.891。两组D90差值分别为(3.1±2.4) Gy和(10.0±8.7) Gy，-2.5，0.012。两组D90百分比差值分别为3.1%±1.9%和9.5%±7.9%，与传统组比较，模板组波动较小，差异有统计学意义(-2.7，0.006)(均P<0.05)。三维模板引导下粒子植入术后装计划与预计划剂量参数基本一致。三维模板重复性好，为三维打印技术的推广提供了理论依据。
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