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全膝关节置换术后血红蛋白浓度测定的最佳时机:术后第1天与第2天的比较。

Optimal Timing for Hemoglobin Concentration Determination after Total Knee Arthroplasty: Day 1 versus Day 2.

作者信息

Khalfaoui Mahdi Yacine, Godavitarne Charles, Wilkinson Michael C P

机构信息

Department of Trauma and Orthopaedics, Salford Royal NHS Foundation Trust, Salford, UK.

Department of Trauma and Orthopaedics, King's College Hospital, London, UK.

出版信息

Knee Surg Relat Res. 2017 Mar 1;29(1):52-56. doi: 10.5792/ksrr.16.038.

Abstract

PURPOSE

Postoperative hemoglobin (Hb) determination remains an essential parameter for quantifying blood loss following total knee replacement (TKR) surgery and guiding transfusion practice. In this study we aimed to ascertain the optimal timing for Hb determination postoperatively and assess its relationship to serum hematocrit (Hct).

MATERIALS AND METHODS

This was a retrospective cohort analysis of 61 consecutive patients undergoing preoperative, day 1 and day 2 Hb and Hct concentration determination following TKR surgery. This was a single centre study in the United Kingdom.

RESULTS

The mean fall in Hb concentration at day 1 was 2.9 g/dL in comparison to 3.3 g/dL at day 2. This indicated a significant difference of 0.39 g/dL (p=0.023). A total of 5 patients required blood transfusions following day 2 Hb determination. Postoperative Hct values varied in close relation with the Hb concentration with no significant differences demonstrated. Our study reveals a significant change between day 1 and day 2 Hb concentrations following TKR surgery, with no significant differing information provided through Hct determination.

CONCLUSIONS

Our results support the use of delayed routine testing at day 2 following surgery as it is likely to more accurately reflect ongoing hidden blood loss into the joint cavity and within soft tissue planes.

摘要

目的

术后血红蛋白(Hb)测定仍然是全膝关节置换术(TKR)后量化失血以及指导输血实践的重要参数。在本研究中,我们旨在确定术后Hb测定的最佳时机,并评估其与血清血细胞比容(Hct)的关系。

材料与方法

这是一项对61例连续接受TKR手术患者进行术前、术后第1天和第2天Hb和Hct浓度测定的回顾性队列分析。这是在英国进行的一项单中心研究。

结果

术后第1天Hb浓度平均下降2.9 g/dL,而术后第2天为3.3 g/dL。这表明两者存在显著差异,差值为0.39 g/dL(p=0.023)。共有5例患者在术后第2天测定Hb后需要输血。术后Hct值与Hb浓度密切相关,未显示出显著差异。我们的研究揭示了TKR手术后第1天和第2天Hb浓度存在显著变化,通过Hct测定未提供显著不同的信息。

结论

我们的结果支持在术后第2天进行延迟常规检测,因为这可能更准确地反映关节腔和软组织平面持续存在的隐性失血情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8b2/5336371/4ee15707af2d/ksrr-29-052f1.jpg

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