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使用较低或较高的血红蛋白阈值进行红细胞输血的结果。

Outcomes using lower vs higher hemoglobin thresholds for red blood cell transfusion.

机构信息

Division of General Internal Medicine, UMDNJ-Robert Wood Johnson Medical School, 125 Paterson St, New Brunswick, NJ 08903, USA.

出版信息

JAMA. 2013 Jan 2;309(1):83-4. doi: 10.1001/jama.2012.50429.

DOI:10.1001/jama.2012.50429
PMID:23280228
Abstract

CLINICAL QUESTION

Is a lower vs higher hemoglobin threshold best for minimizing both red blood cell use and adverse clinical outcomes when used to trigger red blood cell transfusions in anemic patients in critical care and acute care settings?

BOTTOM LINE

Compared with higher hemoglobin thresholds, a hemoglobin threshold of 7 or 8 g/dL is associated with fewer red blood cell units transfused without adverse associations with mortality, cardiac morbidity, functional recovery, or length of hospital stay.

摘要

临床问题

在重症监护和急性护理环境中,为贫血患者输血时,较低的血红蛋白阈值与较高的血红蛋白阈值相比,哪个更能减少红细胞的使用并降低不良临床结局的风险?

结论

与较高的血红蛋白阈值相比,血红蛋白阈值为 7 或 8 g/dL 与输注的红细胞单位数减少相关,而与死亡率、心脏发病率、功能恢复或住院时间无不良关联。

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