Krogager Christoffer, Laugesen Esben, Rossen Niklas B, Poulsen Per L, Erlandsen Mogens, Hansen Klavs W
aDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital bDepartment of Clinical Medicine cSection for Biostatistics, Department of Public Health, Aarhus University, Aarhus dDiagnostic Centre, Silkeborg Regional Hospital, Silkeborg eThe Danish Diabetes Academy, Odense University Hospital, Odense, Denmark.
Blood Press Monit. 2017 Jun;22(3):161-165. doi: 10.1097/MBP.0000000000000246.
The aim of this study was to evaluate the usefulness of Microlife WatchBP Office and the effect of increasing the number of measurements in the clinical evaluation of systolic interarm difference (IAD).
Office blood pressure was measured simultaneously on both arms in 339 patients (85% diabetic) using the Microlife WatchBP Office, a fully automatic, oscillometric device. The patients included were all scheduled for ambulatory blood pressure measurement at the outpatient clinic of endocrinology at Silkeborg Regional Hospital, Denmark. Two successive sets of three individual measurements were made. A statistical analysis of variance was carried out on the measurements.
In the first set of measurements, the mean IAD was -0.3 mmHg and the prevalence of IAD greater than or equal to 10 mmHg was 9.1%. Only 7.6% of the patients with an IAD less than 10 mmHg in the first set of measurements had an IAD greater than or equal to 10 mmHg in the second set of measurements. The 95% limits of agreement for the mean IAD for a single set of three measurements were ±13.16 mmHg. The probability of detecting an IAD more than 10 mmHg only increased slightly with an increasing number of measurements.
A single set of triplicate measurements using Microlife WatchBP is an acceptable method for evaluating IAD as more measurements do little to improve the probability of detecting an IAD more than 10 mmHg because of high intraindividual variation.
本研究旨在评估Microlife WatchBP Office的实用性以及增加测量次数对收缩期双臂血压差值（IAD）临床评估的影响。
使用Microlife WatchBP Office（一种全自动示波装置）对339例患者（85%为糖尿病患者）的双臂同时进行诊室血压测量。纳入的患者均计划在丹麦锡尔克堡地区医院内分泌门诊进行动态血压测量。连续进行两组，每组三次独立测量。对测量结果进行方差统计分析。
在第一组测量中，平均IAD为-0.3 mmHg，IAD大于或等于10 mmHg的患病率为9.1%。在第一组测量中IAD小于10 mmHg的患者中，只有7.6%在第二组测量中IAD大于或等于10 mmHg。一组三次测量的平均IAD的95%一致性界限为±13.16 mmHg。随着测量次数增加，检测到IAD大于10 mmHg的概率仅略有增加。
由于个体内差异较大，使用Microlife WatchBP进行一组三次重复测量是评估IAD的可接受方法，因为增加测量次数对检测到IAD大于10 mmHg的概率改善不大。
