存在耳蜗负载时盖膜行波的几何要求。
Geometric Requirements for Tectorial Membrane Traveling Waves in the Presence of Cochlear Loads.
作者信息
Sellon Jonathan B, Ghaffari Roozbeh, Freeman Dennis M
机构信息
Harvard-MIT Program in Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts; Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts.
Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts.
出版信息
Biophys J. 2017 Mar 28;112(6):1059-1062. doi: 10.1016/j.bpj.2017.02.002. Epub 2017 Feb 22.
Recent studies suggest that wave motions of the tectorial membrane (TM) play a critical role in determining the frequency selectivity of hearing. However, frequency tuning is also thought to be limited by viscous loss in subtectorial fluid. Here, we analyze effects of this loss and other cochlear loads on TM traveling waves. Using a viscoelastic model, we demonstrate that hair bundle stiffness has little effect on TM traveling waves calculated with physiological parameters, that the limbal attachment can cause small (<20%) increases in TM wavelength, and that viscous loss in the subtectorial fluid can cause small (<20%) decreases in TM wave decay constants. However, effects of viscous loss in the subtectorial fluid are significantly increased if TM thickness is decreased. In contrast, increasing TM thickness above its physiological range has little effect on the wave, suggesting that the TM is just thick enough to maximize the spatial extent of the TM traveling wave.
最近的研究表明，盖膜（TM）的波动在决定听力的频率选择性方面起着关键作用。然而，频率调谐也被认为受到盖膜下液体粘性损失的限制。在这里，我们分析这种损失和其他耳蜗负载对TM行波的影响。使用粘弹性模型，我们证明毛束刚度对用生理参数计算的TM行波影响很小，角膜缘附着可使TM波长小幅增加（<20%），盖膜下液体的粘性损失可使TM波衰减常数小幅降低（<20%）。然而，如果TM厚度减小，盖膜下液体粘性损失的影响会显著增加。相比之下，将TM厚度增加到其生理范围以上对波的影响很小，这表明TM的厚度刚好足以使TM行波的空间范围最大化。
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