Tang K N, Fletcher O J, Villegas P
Tennessee Department of Agriculture, Ellington Agriculture Center, Nashville 37204.
Avian Dis. 1987 Jul-Sep;31(3):577-83.
Reovirus strains CO8 and 81-5, isolated from chickens with malabsorption syndrome, and reovirus strain 176, isolated from chickens with tenosynovitis, were each individually inoculated into 1-day-old specific-pathogen-free chicks. Strain CO8 caused tenosynovitis and pericarditis following footpad inoculation, but it was of low pathogenicity when given by either oral or subcutaneous route. In contrast, strains 81-5 and 176 were highly pathogenic and caused severe mortality following subcutaneous inoculation. Lesions included hepatic necrosis, bursal atrophy, thymitis, and splenic hyperplasia; strain 81-5 also caused pericarditis and myocarditis. Although strain 176 caused higher mortality than strain 81-5, these two strains differed little in the severity and distribution of the lesions they caused. No signs or lesions of typical malabsorption syndrome were observed.
从患有吸收不良综合征的鸡中分离出的呼肠孤病毒株CO8和81 - 5，以及从患有腱鞘炎的鸡中分离出的呼肠孤病毒株176，分别单独接种到1日龄无特定病原体的雏鸡中。CO8株经脚垫接种后引起腱鞘炎和心包炎，但经口服或皮下途径接种时致病性较低。相比之下，81 - 5株和176株具有高致病性，皮下接种后导致严重死亡。病变包括肝坏死、法氏囊萎缩、胸腺炎和脾增生；81 - 5株还引起心包炎和心肌炎。虽然176株比81 - 5株导致的死亡率更高，但这两种毒株在其所引起病变的严重程度和分布方面差异不大。未观察到典型吸收不良综合征的体征或病变。
