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镧在胃中的沉积:扫描电子显微镜对其检测的实用性

Lanthanum Deposition in the Stomach: Usefulness of Scanning Electron Microscopy for Its Detection.

作者信息

Iwamuro Masaya, Urata Haruo, Tanaka Takehiro, Ando Akemi, Nada Takahiro, Kimura Kosuke, Yamauchi Kenji, Kusumoto Chiaki, Otsuka Fumio, Okada Hiroyuki

机构信息

Departments of Gastroenterology and Hepatology, General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558,

出版信息

Acta Med Okayama. 2017 Feb;71(1):73-78. doi: 10.18926/AMO/54828.

Abstract

After having been treated with lanthanum carbonate administration for 4 years for hyperphosphatemia, a 75-year-old Japanese woman undergoing hemodialysis was diagnosed with lanthanum phosphate deposition in the stomach. The deposition, seen as white microgranules, was observed using esophagogastroduodenoscopy with magnifying observation. To the best of our knowledge, these are the minutest endoscopy images of lanthanum phosphate deposition in the gastric mucosa. Scanning electron microscopy (SEM) observation enabled easier identification of the deposited material, which was visible as bright areas. The present case suggests the usefulness of SEM observation in the detection of lanthanum phosphate deposition in the gastrointestinal tract.

摘要

一名75岁接受血液透析的日本女性因高磷血症接受碳酸镧治疗4年后,被诊断出胃内有磷酸镧沉积。通过放大观察的食管胃十二指肠镜检查观察到这种沉积,表现为白色微粒。据我们所知,这些是胃黏膜中磷酸镧沉积的最小内镜图像。扫描电子显微镜(SEM)观察使沉积物质更容易识别,其表现为明亮区域。本病例表明SEM观察在检测胃肠道中磷酸镧沉积方面的有用性。

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