Massey Jennifer
Department of Neurology, Royal North Shore Hospital, St Leonards, Sydney, NSW 2006, Australia.
J Clin Neurosci. 2017 Jun;40:57-59. doi: 10.1016/j.jocn.2017.01.005. Epub 2017 Feb 24.
PRES is a neurological syndrome characterised by reversible subcortical vasogenic brain oedema in patients with acute neurological signs and symptoms. It occurs in the context of fluctuations in blood pressure, renal failure, autoimmune disorders, eclamptic syndromes and with use of cytotoxic drugs. We present the case of a 60year old female with advanced bowel cancer who was admitted with seizures and sub-arachnoid haemorrhage, with radiographic features of PRES, shortly after receiving bevacizumab (Avastin), a VEGF-inhibitor.
后部可逆性脑病综合征（PRES）是一种神经综合征，其特征为急性神经体征和症状患者出现可逆性皮质下血管源性脑水肿。它发生于血压波动、肾衰竭、自身免疫性疾病、子痫综合征以及使用细胞毒性药物的情况下。我们报告一例60岁晚期肠癌女性患者，在接受血管内皮生长因子（VEGF）抑制剂贝伐单抗（阿瓦斯汀）后不久，因癫痫发作和蛛网膜下腔出血入院，具有PRES的影像学特征。
