应用 FDG PET/CT 监测广泛骨结节状类肉瘤病的治疗。

Monitoring the Therapy of Extensive Osseous Sarcoidosis With FDG PET/CT.

机构信息

From the *Department of Nuclear Medicine, American Hospital, Dubai, United Arab Emirates; and †Department of Pulmonary and Respiratory Critical Care Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

出版信息

Clin Nucl Med. 2017 Jul;42(7):e337-e339. doi: 10.1097/RLU.0000000000001598.

DOI:10.1097/RLU.0000000000001598

PMID:28240658

Abstract

FDG PET/CT was performed in a 47-year-old man to evaluate possible malignancy of the spine revealed by MRI. The PET images revealed numerous focal FDG activity throughout the skeletal system. In addition, multiple foci of the increased activity in the mediastinal and hilar nodes were noted, suggestive of sarcoidosis, which was proven following biopsy. Therapy for sarcoidosis was initiated. In the subsequent 4 follow-up FDG PET/CT scans, the activity in both the bones and mediastinal/hilar regions fluctuated. However, anatomical abnormality in the bones on the CT images was never visualized during the entire clinical course.

摘要

一位 47 岁男性因 MRI 显示脊柱可能存在恶性肿瘤而进行 FDG PET/CT 检查。PET 图像显示骨骼系统内存在多处局灶性 FDG 活性增高。此外，纵隔和肺门淋巴结的活性也有多处增高，提示结节病，活检后证实了这一诊断。结节病的治疗随即开始。在随后的 4 次 FDG PET/CT 随访扫描中，骨骼和纵隔/肺门区域的活性均有波动。然而，在整个临床过程中，CT 图像上的骨骼解剖结构异常从未被观察到。