Imhof M, Schmidt E, Bruch H P, Oppelt M, Conrad F, Döll W
Chirurgische Universitätsklinik Würzburg.
Chirurg. 1987 Sep;58(9):590-3.
The diffuse peritonitis is a syndrome during the course of which biochemical reactive chains are activated according to a cascade principle. Most of these biochemical reactive chains develop within an acid environment. The solutions applied for abdominal lavage so far had neutral pH value. The present acute peritonitis experiment has shown that a peritoneal pH increase during lavage therapy stopped the septic reactive chain and thus improved significantly the rate of survival in the test animals. These experimental findings ar now subject for clinical examination.
弥漫性腹膜炎是一种综合征，在此过程中，生化反应链会按照级联原理被激活。这些生化反应链大多在酸性环境中发展。迄今为止，用于腹腔灌洗的溶液pH值呈中性。目前的急性腹膜炎实验表明，灌洗治疗期间腹膜pH值升高可阻止感染性反应链，从而显著提高实验动物的存活率。这些实验结果目前有待临床检验。
