[禽肉瘤病毒转化的大鼠细胞系中的前病毒结构与表达]
[Provirus structure and expression in rat cell lines transformed by the avian sarcoma virus].
作者信息
Brashishkite D A, Galetskiĭ S A, Kulifeĭ P, Urbanchikova M, Lizonova A
出版信息
Eksp Onkol. 1987;9(4):22-6.
PMID:2824174
Abstract
Two type of exogenous action on transformed cells have been investigated. The first system includes clones of TWERC cells transformed by Rous sarcoma virus and cultivated in the presence of 5-bromodeoxyuridine. The second system consists of spontaneously transformed rat cells Sam IV superinfected with avian sarcoma virus B-77. In these cell lines and clones the structure of the provirus and its expression have been analyzed by different molecular probes.
摘要
已对转化细胞的两种外源作用类型进行了研究。第一个系统包括由劳氏肉瘤病毒转化并在5-溴脱氧尿苷存在下培养的TWERC细胞克隆。第二个系统由被禽肉瘤病毒B-77超感染的自发转化大鼠细胞Sam IV组成。在这些细胞系和克隆中，已通过不同的分子探针分析了前病毒的结构及其表达。
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