Cohen Evan T, Kietrys David, Fogerite Susan Gould, Silva Mariella, Logan Kristen, Barone Donald A, Parrott J Scott
Int J MS Care. 2017 Jan-Feb;19(1):30-39. doi: 10.7224/1537-2073.2015-046.
This pilot study determined the feasibility of a specifically designed 8-week yoga program for people with moderate multiple sclerosis (MS)-related disability. We explored the program's effect on quality of life (QOL) and physical and mental performance.
We used a single-group design with repeated measurements at baseline, postintervention, and 8-week follow-up. Feasibility was examined through cost, recruitment, retention, attendance, and safety. Outcomes included the Multiple Sclerosis Quality of Life Inventory (MSQLI), 12-item Multiple Sclerosis Walking Scale (MSWS-12), Timed 25-Foot Walk test (T25FW), 6-Minute Walk Test (6MWT), Nine-Hole Peg Test (NHPT), Five-Times Sit-to-Stand Test (FTSTS), Multidirectional Reach Test (MDRT), maximum expiratory pressure, and Paced Auditory Serial Addition Test-3″ (PASAT-3″).
Fourteen participants completed the study. The program was feasible. There were significant main effects on the 36-item Short Form Health Status Survey Mental Component Summary (SF-36 MCS), Modified Fatigue Impact Scale (MFIS), Bladder Control Scale (BLCS), Perceived Deficits Questionnaire (PDQ), Mental Health Inventory (MHI), MSWS-12, T25FW, NHPT, PASAT-3″, 6MWT, FTSTS, and MDRT-Back. Improvements were found on the SF-36 MCS, MFIS, BLCS, PDQ, MHI, and MSWS-12 between baseline and postintervention. The effect on PDQ persisted at follow-up. Improvements were found on the T25FW, NHPT, 6MWT, FTSTS, and MDRT-Back between baseline and postintervention that persisted at follow-up. The PASAT-3″ did not change between baseline and postintervention but did between postintervention and follow-up.
The yoga program was safe and feasible. Improvements in certain measures of QOL and performance were seen at postintervention and follow-up.
这项试点研究确定了一项专门设计的为期8周的瑜伽计划对于中度多发性硬化症（MS）相关残疾患者的可行性。我们探讨了该计划对生活质量（QOL）以及身体和心理表现的影响。
我们采用单组设计，在基线、干预后和8周随访时进行重复测量。通过成本、招募、留存率、出勤率和安全性来检验可行性。结果指标包括多发性硬化症生活质量量表（MSQLI）、12项多发性硬化症步行量表（MSWS-12）、25英尺定时步行测试（T25FW）、6分钟步行测试（6MWT）、九孔插板测试（NHPT）、五次坐立测试（FTSTS）、多方向伸展测试（MDRT）、最大呼气压力以及3秒听觉连续加法测试（PASAT-3″）。
14名参与者完成了研究。该计划是可行的。在36项简短健康状况调查问卷心理成分总结（SF-36 MCS）、改良疲劳影响量表（MFIS）、膀胱控制量表（BLCS）、感知缺陷问卷（PDQ）、心理健康量表（MHI）、MSWS-12、T25FW、NHPT、PASAT-3″、6MWT、FTSTS和MDRT-背部方面存在显著的主效应。在基线和干预后之间，SF-36 MCS、MFIS、BLCS、PDQ、MHI和MSWS-12有改善。对PDQ的影响在随访时持续存在。在基线和干预后之间，T25FW、NHPT、6MWT、FTSTS和MDRT-背部有改善，且在随访时持续存在。PASAT-3″在基线和干预后之间没有变化，但在干预后和随访之间有变化。
该瑜伽计划是安全可行的。在干预后和随访时，生活质量和表现的某些指标有改善。
