Division of Environmental Health Sciences, College of Public Health, The Ohio State University, Columbus, OH 43210; email:
Department of Food Science and Technology, The Ohio State University, Columbus, OH 43210; email:
Annu Rev Food Sci Technol. 2017 Feb 28;8:281-304. doi: 10.1146/annurev-food-030216-030116.
A recent ecological study demonstrated a significant association between an increased risk of nonalcoholic liver disease mortality and freshwater cyanobacterial blooms. Moreover, previous epidemiology studies highlighted a relationship between cyanotoxins in drinking water with liver cancer and damage and colorectal cancer. These associations identified cyanobacterial blooms as a global public health and environmental problem, affecting freshwater bodies that are important sources for drinking water, agriculture, and aquafarms. Furthermore, as a result of climate change, it is expected that our freshwater environments will become more favorable for producing harmful blooms that produce various cyanotoxins. Food is an important source of cyanotoxin exposure to humans, but it has been less addressed. This paper synthesizes information from the studies that have investigated cyanotoxins in freshwater and food on a global scale. We also review and summarize the health effects and exposure routes of cyanotoxins and candidates for cyanotoxin treatment methods that can be applied to food.
最近的一项生态学研究表明,非酒精性肝病死亡率的增加与淡水中蓝藻水华的出现之间存在显著关联。此外,先前的流行病学研究强调了饮用水中的蓝藻毒素与肝癌和肝损伤以及结直肠癌之间的关系。这些关联将蓝藻水华确定为一个影响全球公共健康和环境的问题,影响到作为饮用水、农业和水产养殖重要来源的淡水体。此外,由于气候变化,预计我们的淡水环境将更有利于产生产生各种蓝藻毒素的有害水华。食物是人类接触蓝藻毒素的一个重要来源,但这方面的问题研究较少。本文综合了全球范围内研究淡水和食物中蓝藻毒素的信息。我们还回顾和总结了蓝藻毒素的健康影响和暴露途径,以及可应用于食物的蓝藻毒素处理方法的候选物。