相似文献
1
Correcting for cell-type heterogeneity in DNA methylation: a comprehensive evaluation.校正DNA甲基化中的细胞类型异质性：一项综合评估
Nat Methods. 2017 Feb 28;14(3):218-219. doi: 10.1038/nmeth.4190.
2
CpG islands undermethylation in human genomic regions under selective pressure.人类基因组选择性压力区域的 CpG 岛低甲基化。
PLoS One. 2011;6(8):e23156. doi: 10.1371/journal.pone.0023156. Epub 2011 Aug 2.
3
A comparative study for characterisation and prediction of tissue-specific DNA methylation of CpG islands in chromosomes 6, 20 and 22.一项关于6号、20号和22号染色体上CpG岛组织特异性DNA甲基化特征鉴定与预测的比较研究。
Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:1832-5. doi: 10.1109/IEMBS.2010.5626437.
4
Stabilization of epigenetic states of CpG islands by local cooperation.通过局部协作实现CpG岛表观遗传状态的稳定
Mol Biosyst. 2016 Jun 21;12(7):2142-6. doi: 10.1039/c6mb00044d.
5
Distribution of DNA methylation, CpGs, and CpG islands in human isochores.人类同型区中的 DNA 甲基化、CpG 及其岛的分布。
Genomics. 2010 Jan;95(1):25-8. doi: 10.1016/j.ygeno.2009.09.006. Epub 2009 Oct 1.
6
Deoxyribonucleic acid methylation profiling of single human blastocysts by methylated CpG-island amplification coupled with CpG-island microarray.通过甲基化CpG岛扩增结合CpG岛微阵列对单个人类囊胚进行脱氧核糖核酸甲基化分析。
Fertil Steril. 2015 Jun;103(6):1566-71.e1-4. doi: 10.1016/j.fertnstert.2015.03.020. Epub 2015 Apr 22.
7
Methylation Analysis of CpG Islands in Pineapple Promoter.菠萝启动子中CpG岛的甲基化分析
Genes (Basel). 2020 Apr 15;11(4):425. doi: 10.3390/genes11040425.
8
Integration of CpG-free DNA induces de novo methylation of CpG islands in pluripotent stem cells.无CpG DNA的整合诱导多能干细胞中CpG岛的从头甲基化。
Science. 2017 May 5;356(6337):503-508. doi: 10.1126/science.aag3260.
9
Programming of DNA methylation in type 2 diabetes.2型糖尿病中DNA甲基化的编程
Diabetologia. 2013 May;56(5):947-8. doi: 10.1007/s00125-013-2866-4. Epub 2013 Mar 6.
10
CpG islands: algorithms and applications in methylation studies.CpG岛：甲基化研究中的算法与应用
Biochem Biophys Res Commun. 2009 May 15;382(4):643-5. doi: 10.1016/j.bbrc.2009.03.076. Epub 2009 Mar 18.
引用本文的文献
1
A review of the use of tumour DNA methylation for breast cancer subtyping and prediction of outcomes.肿瘤DNA甲基化在乳腺癌亚型分类及预后预测中的应用综述。
Clin Epigenetics. 2025 Jul 2;17(1):109. doi: 10.1186/s13148-025-01922-z.
2
Reference-free deconvolution of complex samples based on cross-cell-type differential analysis: Systematic evaluations with various feature selection options.基于跨细胞类型差异分析的复杂样本无参考去卷积：使用各种特征选择选项的系统评估
Front Genet. 2025 May 30;16:1570781. doi: 10.3389/fgene.2025.1570781. eCollection 2025.
3
Targeting the hypothalamus for modeling age-related DNA methylation and developing OXT-GnRH combinational therapy against Alzheimer's disease-like pathologies in male mouse model.针对下丘脑进行建模以研究与年龄相关的 DNA 甲基化，并开发针对男性小鼠模型中阿尔茨海默病样病理的 OXT-GnRH 联合治疗方法。
Nat Commun. 2024 Oct 31;15(1):9419. doi: 10.1038/s41467-024-53507-8.
4
Targeted Methylation Profiling of Single Laser-Capture Microdissected Post-Mortem Brain Cells by Adapted Limiting Dilution Bisulfite Pyrosequencing (LDBSP).采用改良的限制性稀释亚硫酸氢盐焦磷酸测序法（LDBSP）对激光捕获微切割死后脑组织细胞进行靶向甲基化分析。
Int J Mol Sci. 2022 Dec 8;23(24):15571. doi: 10.3390/ijms232415571.
5
Multiomic Signatures of Chronic Beryllium Disease Bronchoalveolar Lavage Cells Relate to T-Cell Function and Innate Immunity.多组学特征分析慢性铍病支气管肺泡灌洗液细胞与 T 细胞功能和固有免疫有关。
Am J Respir Cell Mol Biol. 2022 Dec;67(6):632-640. doi: 10.1165/rcmb.2022-0077OC.
6
Associations between antenatal maternal asthma status and placental DNA methylation.产前母亲哮喘状况与胎盘 DNA 甲基化之间的关联。
Placenta. 2022 Aug;126:184-195. doi: 10.1016/j.placenta.2022.06.008. Epub 2022 Jul 3.
7
Using R for Cell-Type Composition Imputation in Epigenome-Wide Association Studies.使用 R 进行表观基因组关联研究中的细胞类型组成推断。
Methods Mol Biol. 2022;2432:49-56. doi: 10.1007/978-1-0716-1994-0_4.
8
DNA methylation changes in cord blood and the developmental origins of health and disease - a systematic review and replication study.脐带血中的 DNA 甲基化变化与健康和疾病的发育起源——系统评价和复制研究。
BMC Genomics. 2022 Mar 19;23(1):221. doi: 10.1186/s12864-022-08451-6.
9
Detecting cord blood cell type-specific epigenetic associations with gestational diabetes mellitus and early childhood growth.检测脐带血细胞类型特异性的与妊娠糖尿病和儿童早期生长相关的表观遗传关联。
Clin Epigenetics. 2021 Jun 26;13(1):131. doi: 10.1186/s13148-021-01114-5.
10
Determining subpopulation methylation profiles from bisulfite sequencing data of heterogeneous samples using DXM.使用 DXM 从异质样本的亚硫酸盐测序数据中确定亚群甲基化谱。
Nucleic Acids Res. 2021 Sep 20;49(16):e93. doi: 10.1093/nar/gkab516.
本文引用的文献
1
Correcting for cell-type heterogeneity in epigenome-wide association studies: revisiting previous analyses.在全表观基因组关联研究中校正细胞类型异质性：重新审视以往分析。
Nat Methods. 2017 Feb 28;14(3):216-217. doi: 10.1038/nmeth.4187.
2
An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation.精神分裂症的综合遗传-表观遗传分析：遗传关联与DNA甲基化差异共定位的证据
Genome Biol. 2016 Aug 30;17(1):176. doi: 10.1186/s13059-016-1041-x.
3
Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies.稀疏主成分分析在全表观基因组关联研究中校正细胞类型异质性。
Nat Methods. 2016 May;13(5):443-5. doi: 10.1038/nmeth.3809. Epub 2016 Mar 28.
4
Improving cell mixture deconvolution by identifying optimal DNA methylation libraries (IDOL).通过识别最佳DNA甲基化文库（IDOL）改善细胞混合物反卷积
BMC Bioinformatics. 2016 Mar 8;17:120. doi: 10.1186/s12859-016-0943-7.
5
DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer.正常乳腺组织中的DNA甲基化异常值可识别出在癌症中富集的场缺陷。
Nat Commun. 2016 Jan 29;7:10478. doi: 10.1038/ncomms10478.
6
Epigenetic signature of birth weight discordance in adult twins.成年双胞胎出生体重不一致的表观遗传特征。
BMC Genomics. 2014 Dec 4;15(1):1062. doi: 10.1186/1471-2164-15-1062.
7
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis.全基因组关联数据表明 DNA 甲基化是类风湿关节炎遗传风险的中介。
Nat Biotechnol. 2013 Feb;31(2):142-7. doi: 10.1038/nbt.2487. Epub 2013 Jan 20.
8
DNA methylation arrays as surrogate measures of cell mixture distribution.DNA 甲基化芯片作为细胞混合物分布的替代测量指标。
BMC Bioinformatics. 2012 May 8;13:86. doi: 10.1186/1471-2105-13-86.
9
Independent surrogate variable analysis to deconvolve confounding factors in large-scale microarray profiling studies.独立的替代变量分析可在大规模微阵列分析研究中去卷积混杂因素。
Bioinformatics. 2011 Jun 1;27(11):1496-505. doi: 10.1093/bioinformatics/btr171. Epub 2011 Apr 6.
10
Capturing heterogeneity in gene expression studies by surrogate variable analysis.通过替代变量分析在基因表达研究中捕捉异质性。
PLoS Genet. 2007 Sep;3(9):1724-35. doi: 10.1371/journal.pgen.0030161. Epub 2007 Aug 1.
Zotero 插件