Suppr超能文献

维生素A补充计划与国家层面维生素A缺乏的证据

Vitamin A Supplementation Programs and Country-Level Evidence of Vitamin A Deficiency.

作者信息

Wirth James P, Petry Nicolai, Tanumihardjo Sherry A, Rogers Lisa M, McLean Erin, Greig Alison, Garrett Greg S, Klemm Rolf D W, Rohner Fabian

机构信息

GroundWork, 7306 Fläsch, Switzerland.

Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA.

出版信息

Nutrients. 2017 Feb 24;9(3):190. doi: 10.3390/nu9030190.

Abstract

Vitamin A supplementation (VAS) programs targeted at children aged 6-59 months are implemented in many countries. By improving immune function, vitamin A (VA) reduces mortality associated with measles, diarrhea, and other illnesses. There is currently a debate regarding the relevance of VAS, but amidst the debate, researchers acknowledge that the majority of nationally-representative data on VA status is outdated. To address this data gap and contribute to the debate, we examined data from 82 countries implementing VAS programs, identified other VA programs, and assessed the recentness of national VA deficiency (VAD) data. We found that two-thirds of the countries explored either have no VAD data or data that were >10 years old (i.e., measured before 2006), which included twenty countries with VAS coverage ≥70%. Fifty-one VAS programs were implemented in parallel with at least one other VA intervention, and of these, 27 countries either had no VAD data or data collected in 2005 or earlier. To fill these gaps in VAD data, countries implementing VAS and other VA interventions should measure VA status in children at least every 10 years. At the same time, the coverage of VA interventions can also be measured. We identified three countries that have scaled down VAS, but given the lack of VA deficiency data, this would be a premature undertaking in most countries without appropriate status assessment. While the global debate about VAS is important, more attention should be directed towards individual countries where programmatic decisions are made.

摘要

许多国家都实施了针对6至59个月大儿童的维生素A补充(VAS)计划。通过改善免疫功能,维生素A(VA)可降低与麻疹、腹泻及其他疾病相关的死亡率。目前关于VAS的相关性存在争议,但在这场争论中,研究人员承认,大多数关于VA状况的全国代表性数据已经过时。为了填补这一数据空白并为这场争论提供参考,我们研究了82个实施VAS计划的国家的数据,确定了其他VA计划,并评估了国家VA缺乏(VAD)数据的时效性。我们发现,三分之二被研究的国家要么没有VAD数据,要么数据超过10年(即2006年之前测量),其中包括20个VAS覆盖率≥70%的国家。51个VAS计划与至少一项其他VA干预措施同时实施,其中27个国家要么没有VAD数据,要么数据是在2005年或更早收集的。为了填补VAD数据的这些空白,实施VAS和其他VA干预措施的国家应至少每10年测量一次儿童的VA状况。同时,也可以测量VA干预措施的覆盖率。我们确定了三个已经缩减VAS规模的国家,但由于缺乏VA缺乏数据,在大多数没有进行适当状况评估的国家,这将是一项为时过早的举措。虽然关于VAS的全球争论很重要,但更多的注意力应放在做出计划决策的各个国家上。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验