Bischoff-Ferrari Heike A
Geriatric Clinic, University Hospital Zurich, Centre on aging and mobility, University of Zurich and City Hospital Waid, University Hospital Zurich, Switzerland.
Geriatr Psychol Neuropsychiatr Vieil. 2017 Mar 1;15(1):E1-E7. doi: 10.1684/pnv.2017.0650.
This review will summarize recent clinical studies and meta-analyses on the effect of vitamin D supplementation on fall prevention. As fall prevention is fundamental in fracture prevention at older age, we discuss if and to what extend the vitamin D effect on muscle modulates hip fracture risk. Further, to explain the effect of vitamin D on fall prevention, we will review the mechanistic evidence linking vitamin D to muscle health and the potentially selective effect of vitamin D on type II fast muscle fibers.
本综述将总结近期关于补充维生素D对预防跌倒效果的临床研究和荟萃分析。由于预防跌倒是预防老年人骨折的基础,我们将探讨维生素D对肌肉的作用是否以及在多大程度上调节髋部骨折风险。此外,为了解释维生素D对预防跌倒的作用,我们将回顾将维生素D与肌肉健康联系起来的机制证据,以及维生素D对II型快肌纤维的潜在选择性作用。