Kim Seung Kwon, Lee Kristen A, Sauk Steven, Korenblat Kevin
Interventional Radiology, Mallinckrodt Institute of Radiology, Washington University St. Louis School of Medicine, St. Louis, MO 63110, USA.; Department of Radiology, Kyung Hee University College of Medicine, Seoul 02447, Korea.
Interventional Radiology, Mallinckrodt Institute of Radiology, Washington University St. Louis School of Medicine, St. Louis, MO 63110, USA.
Korean J Radiol. 2017 Mar-Apr;18(2):345-354. doi: 10.3348/kjr.2017.18.2.345. Epub 2017 Feb 7.
Although a transjugular intrahepatic portosystemic shunt (TIPS) is commonly placed to manage isolated gastric varices, balloon-occluded retrograde transvenous obliteration (BRTO) has also been used. We compare the long-term outcomes from these procedures based on our institutional experience.
We conducted a retrospective review of patients with isolated gastric varices who underwent either TIPS with a covered stent or BRTO between January 2000 and July 2013. We identified 52 consecutive patients, 27 who had received TIPS with a covered stent and 25 who had received BRTO. We compared procedural complications, re-bleeding rates, and clinical outcomes between the two groups.
There were no significant differences in procedural complications between patients who underwent TIPS (7%) and those who underwent BRTO (12%) ( = 0.57). There were also no statistically significant differences in re-bleeding rates from gastric varices between the two groups (TIPS, 7% [2/27]; BRTO, 8% [2/25]; = 0.94) or in developing new ascites following either procedure (TIPS, 4%; BRTO, 4%; = 0.96); significantly more patients who underwent TIPS developed hepatic encephalopathy (22%) than did those who underwent BRTO (0%, = 0.01). There was no statistically significant difference in mean survival between the two groups (TIPS, 30 months; BRTO, 24 months; = 0.16); median survival for the patients who received TIPS was 16.6 months, and for those who underwent BRTO, it was 26.6 months.
BRTO is an effective method of treating isolated gastric varices with similar outcomes and complication rates to those of TIPS with a covered stent but with a lower rate of hepatic encephalopathy.
虽然经颈静脉肝内门体分流术(TIPS)常用于治疗孤立性胃静脉曲张,但球囊闭塞逆行静脉栓塞术(BRTO)也已被应用。我们根据本机构的经验比较了这些手术的长期疗效。
我们对2000年1月至2013年7月期间接受带覆膜支架的TIPS或BRTO治疗的孤立性胃静脉曲张患者进行了回顾性研究。我们确定了52例连续患者,其中27例接受了带覆膜支架的TIPS治疗,25例接受了BRTO治疗。我们比较了两组的手术并发症、再出血率和临床结局。
接受TIPS治疗的患者(7%)和接受BRTO治疗的患者(12%)在手术并发症方面无显著差异(P = 0.57)。两组胃静脉曲张再出血率(TIPS组为7%[2/27];BRTO组为8%[2/25];P = 0.94)或手术后新发腹水发生率(TIPS组为4%;BRTO组为4%;P = 0.96)也无统计学显著差异;接受TIPS治疗的患者发生肝性脑病的比例(22%)显著高于接受BRTO治疗的患者(0%,P = 0.01)。两组的平均生存期无统计学显著差异(TIPS组为30个月;BRTO组为24个月;P = 0.16);接受TIPS治疗患者的中位生存期为16.6个月,接受BRTO治疗患者的中位生存期为26.6个月。
BRTO是治疗孤立性胃静脉曲张的有效方法,其疗效和并发症发生率与带覆膜支架的TIPS相似,但肝性脑病发生率较低。