Schmidbauer M, Budka H, Bruckner R, Vorkapic P
Neurological Institute, University of Vienna, Austria.
J Neurosurg. 1987 Dec;67(6):915-8. doi: 10.3171/jns.1987.67.6.0915.
The authors report the highly unusual development of a glioblastoma multiforme at the site of excision of a medulloblastoma 6 years earlier. The patient was operated on for a cerebellar medulloblastoma at the age of 13 years. Postoperative treatment included irradiation and chemotherapy. Six years later, a glioblastoma multiforme was found at the original site of the medulloblastoma. Intensive multimodality treatment is considered the likely cause for the later tumor development.
作者报告了1例极为罕见的病例,患者在6年前髓母细胞瘤切除部位发生了多形性胶质母细胞瘤。该患者13岁时因小脑髓母细胞瘤接受手术治疗。术后治疗包括放疗和化疗。6年后,在髓母细胞瘤的原部位发现了多形性胶质母细胞瘤。强化多模式治疗被认为是导致后期肿瘤发生的可能原因。